Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jan 28;9(1):235-238.
doi: 10.4103/jfmpc.jfmpc_715_19. eCollection 2020 Jan.

Clinical, radiographic, and histological findings of chronic inflammatory periapical lesions - A clinical study

Prabu Mahin Syed Ismail  1 , K Apoorva  2 , N Manasa  2 , R Rama Krishna  2 , Siddhartha Bhowmick  3 , Shilpa Jain  4
Affiliations

Clinical, radiographic, and histological findings of chronic inflammatory periapical lesions - A clinical study

Prabu Mahin Syed Ismail et al. J Family Med Prim Care. .

Abstract

Aim: The present study aimed at comparing clinical, radiographical, and histological findings in chronic periapical lesions such as cysts, granuloma, and abscess.

Methodology: The present study was conducted on 148 teeth having chronic inflammatory periapical lesions with or without nonsurgical endodontic treatment. Endodontic surgery was performed by single trained endodontist. After surgical endodontic treatment, biopsy sections of teeth were assessed histologically. All slides stained with hematoxylin/eosin and Gomori trichrome for light microscopy assessment.

Results: Out of 148 teeth, 41 had chronic inflammatory lesions, 34 had inflammatory cysts, and 25 had indefinite lesions. Chronic inflammatory lesions assessed histologically found chronic apical periodontitis in 86 cases and inflammatory cysts in 62 cases. The difference was significant (P < 0.05). Out of 86 cases of chronic apical periodontitis confirmed clinical radiographically, 64% found positive, whereas 36% were not histologically. Out of 62 cases of inflammatory cysts confirmed clinically and radiographically, 78% found positive while 36% were not histologically. Out of 25 indefinite lesions, 56% found chronic inflammatory lesions while 44% found inflammatory cyst.

Conclusion: There was significant disagreement in clinical radiographic as well as histological diagnosis.

Keywords: Clinical; endodontics; histological; lesion radiograph.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Graph 1
Graph 1
Diagnosis of chronic apical periodontitis after clinical radiographic versus histological assessment
Graph 2
Graph 2
Diagnosis of inflammatory cyst after clinical radiographic versus histological examinations
Graph 3
Graph 3
Percentage of chronic apical periodontitis and inflammatory cyst that were diagnosed only by the histological examination
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Patterson SS, Shafer WG, Healey HJ. Periapical lesions associated with endodontically treated teeth. J Am Dent Assoc. 1964;68:191–4. - PubMed
    1. Pulver WH, Taubman MA, Smith DJ. Immune components in human dental periapical lesions. Arch Oral Biol. 1978;23:435–43. - PubMed
    1. Reitschel ET, Brade H. Bacterial endotoxins. Sci Am. 1992;267:26–33. - PubMed
    1. Bhaskar SN. Periapical lesion: Types, incidence, and clinical features. Oral Surg Oral Med Oral Pathol. 1998;21:657–71. - PubMed
    1. Stockdale CR, Chandler NP. The nature of periapical lesion: A review of 1108 cases. J Dent. 1988;16:123–9. - PubMed