Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Nov;8(11):5043-6.
doi: 10.1128/mcb.8.11.5043-5046.1988.

Reproducible and variable rearrangements of a Tetrahymena thermophila surface protein gene family occur during macronuclear development

J P Kile  1 , H D Love Jr, C A Hubach, G A Bannon
Affiliations

Reproducible and variable rearrangements of a Tetrahymena thermophila surface protein gene family occur during macronuclear development

J P Kile et al. Mol Cell Biol. 1988 Nov.

Abstract

The expression of Tetrahymena surface proteins serotype H3 (SerH3) and serotype T (SerT) is under environmental regulation. SerH3 is expressed when cells are incubated between the temperatures of 20 and 35 degrees C, while SerT is expressed when cells are grown at temperatures above 35 degrees C. Using a SerH3 cDNA clone as a hybridization probe, we determined that (i) the SerH3 gene is a member of a multigene family; (ii) most members of this multigene family are variably rearranged during macronuclear development; and (iii) the gene which produces the SerH3 mRNA is reproducibly rearranged during macronuclear development.

PubMed Disclaimer

References

    1. Cell. 1984 Feb;36(2):433-40 - PubMed
    1. Cell. 1984 Feb;36(2):441-5 - PubMed
    1. Nucleic Acids Res. 1984 Feb 24;12(4):1961-75 - PubMed
    1. Nucleic Acids Res. 1986 Feb 11;14(3):1341-54 - PubMed
    1. Mol Cell Biol. 1983 Oct;3(10):1857-65 - PubMed

Publication types

LinkOut - more resources