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. 1988;3(4):333-5.
doi: 10.1002/mds.870030409.

Systemic toxicity of botulinum toxin by intramuscular injection in the monkey

A B Scott  1 , D Suzuki
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Systemic toxicity of botulinum toxin by intramuscular injection in the monkey

A B Scott et al. Mov Disord. 1988.

Abstract

Botulinum toxin (Oculinum) was injected intramuscularly into eight monkeys. The LD50 dose is estimated to be approximately 39 U/kg body weight. The lowest dose that caused systemic toxicity, 33 U/kg, was close to the fatal dose range, 38-42 U/kg.

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