Upfront osimertinib - winner takes it all?
- PMID: 32112056
- DOI: 10.1038/s41571-020-0346-6
Upfront osimertinib - winner takes it all?
Comment on
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Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC.N Engl J Med. 2020 Jan 2;382(1):41-50. doi: 10.1056/NEJMoa1913662. Epub 2019 Nov 21. N Engl J Med. 2020. PMID: 31751012 Clinical Trial.
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- Ramalingam, S. S. et al. Overall survival with osimertinib in untreated, EGFR-mutated advanced NSCLC. N. Engl. J. Med. 382, 41–50 (2020). - DOI
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- Hosomi, Y. et al. Gefitinib alone versus gefitinib plus chemotherapy for non-small-cell lung cancer with mutated epidermal growth factor receptor: NEJ009 study. J. Clin. Oncol. 38, 115–123 (2020). - DOI
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- Wu, Y. L. et al. Overall survival from the AURA 3 phase III study: osimertinib versus platinum-pemetrexed in patients with EGFR T790M advanced NSCLC and progression on prior EGFR TKI. Ann. Oncol. 30, ix157–ix181 (2019). - DOI
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- Ramalingam, S. S. et al. Mechanisms of acquired resistance to first-line osimertinib: preliminary data from the phase III FLAURA study. Ann. Oncol. https://doi.org/10.1093/annonc/mdy424.063 (2018). - DOI - PubMed - PMC
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