COVID-19: combining antiviral and anti-inflammatory treatments

doi:10.1016/S1473-3099(20)30132-8

Comment

. 2020 Apr;20(4):400-402.

doi: 10.1016/S1473-3099(20)30132-8. Epub 2020 Feb 27.

COVID-19: combining antiviral and anti-inflammatory treatments

Justin Stebbing¹, Anne Phelan², Ivan Griffin², Catherine Tucker², Olly Oechsle², Dan Smith², Peter Richardson²

Affiliations

¹ Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK. Electronic address: j.stebbing@imperial.ac.uk.
² Benevolent AI, London, UK.

PMID: 32113509
PMCID: PMC7158903
DOI: 10.1016/S1473-3099(20)30132-8

Comment

COVID-19: combining antiviral and anti-inflammatory treatments

Justin Stebbing et al. Lancet Infect Dis. 2020 Apr.

. 2020 Apr;20(4):400-402.

doi: 10.1016/S1473-3099(20)30132-8. Epub 2020 Feb 27.

Authors

Justin Stebbing¹, Anne Phelan², Ivan Griffin², Catherine Tucker², Olly Oechsle², Dan Smith², Peter Richardson²

Affiliations

¹ Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK. Electronic address: j.stebbing@imperial.ac.uk.
² Benevolent AI, London, UK.

PMID: 32113509
PMCID: PMC7158903
DOI: 10.1016/S1473-3099(20)30132-8

No abstract available

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Comment in

Baricitinib for COVID-19: a suitable treatment?
Favalli EG, Biggioggero M, Maioli G, Caporali R. Favalli EG, et al. Lancet Infect Dis. 2020 Sep;20(9):1012-1013. doi: 10.1016/S1473-3099(20)30262-0. Epub 2020 Apr 3. Lancet Infect Dis. 2020. PMID: 32251638 Free PMC article. No abstract available.
Baricitinib for COVID-19: a suitable treatment? - Authors' reply.
Richardson PJ, Corbellino M, Stebbing J. Richardson PJ, et al. Lancet Infect Dis. 2020 Sep;20(9):1013-1014. doi: 10.1016/S1473-3099(20)30270-X. Epub 2020 Apr 3. Lancet Infect Dis. 2020. PMID: 32251639 Free PMC article. No abstract available.

Comment on

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease.
Richardson P, Griffin I, Tucker C, Smith D, Oechsle O, Phelan A, Rawling M, Savory E, Stebbing J. Richardson P, et al. Lancet. 2020 Feb 15;395(10223):e30-e31. doi: 10.1016/S0140-6736(20)30304-4. Epub 2020 Feb 4. Lancet. 2020. PMID: 32032529 Free PMC article. No abstract available.

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Five severe COVID-19 pneumonia patients treated with triple combination therapy with lopinavir/ritonavir, hydroxychloroquine, and interferon β-1b.
Hong SI, Ryu BH, Chong YP, Lee S, Kim S, Kim HC, Hong KW, Bae IG, Cho OH. Hong SI, et al. Int J Antimicrob Agents. 2020 Aug;56(2):106052. doi: 10.1016/j.ijantimicag.2020.106052. Epub 2020 Jun 13. Int J Antimicrob Agents. 2020. PMID: 32544570 Free PMC article. No abstract available.
Shedding light on therapeutics in alopecia and their relevance to COVID-19.
Fagan N, Meah N, York K, Bokhari L, Fletcher G, Chen G, Tobin DJ, Messenger A, Irvine AD, Sinclair R, Wall D. Fagan N, et al. Clin Dermatol. 2021 Jan-Feb;39(1):76-83. doi: 10.1016/j.clindermatol.2020.12.015. Epub 2020 Dec 16. Clin Dermatol. 2021. PMID: 33972056 Free PMC article.
Randomized double-blind clinical study in patients with COVID-19 to evaluate the safety and efficacy of a phytomedicine (P2Et).
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References

1. Peiris JSM, Chu CM, Cheng VCC, et al. Clinical progression and viral load in a community outbreak or coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed
1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed
1. Richardson P, Griffin I, Tucker C, et al. Baricitinib as potential treatment for 2019-nCoV acute respiratory disease. Lancet. 2020;395:497–506. - PMC - PubMed
1. Segler MHS, Preuss M, Waller P. Planning chemical syntheses with deep neural networks and symbolic AI. Nature. 2018;555:604–610. - PubMed
1. Bekerman E, Neveu G, Shulla A, et al. Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects. J Clin Invest. 2017;127:1338–1352. - PMC - PubMed

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[1] Peiris JSM, Chu CM, Cheng VCC, et al. Clinical progression and viral load in a community outbreak or coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

[2] Peiris JSM, Chu CM, Cheng VCC, et al. Clinical progression and viral load in a community outbreak or coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

[3] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

[4] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

[5] Richardson P, Griffin I, Tucker C, et al. Baricitinib as potential treatment for 2019-nCoV acute respiratory disease. Lancet. 2020;395:497–506. - PMC - PubMed

[6] Richardson P, Griffin I, Tucker C, et al. Baricitinib as potential treatment for 2019-nCoV acute respiratory disease. Lancet. 2020;395:497–506. - PMC - PubMed

[7] Segler MHS, Preuss M, Waller P. Planning chemical syntheses with deep neural networks and symbolic AI. Nature. 2018;555:604–610. - PubMed

[8] Segler MHS, Preuss M, Waller P. Planning chemical syntheses with deep neural networks and symbolic AI. Nature. 2018;555:604–610. - PubMed

[9] Bekerman E, Neveu G, Shulla A, et al. Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects. J Clin Invest. 2017;127:1338–1352. - PMC - PubMed

[10] Bekerman E, Neveu G, Shulla A, et al. Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects. J Clin Invest. 2017;127:1338–1352. - PMC - PubMed

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COVID-19: combining antiviral and anti-inflammatory treatments

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COVID-19: combining antiviral and anti-inflammatory treatments

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