First case of Coronavirus Disease 2019 (COVID-19) pneumonia in Taiwan

doi:10.1016/j.jfma.2020.02.007

Case Reports

. 2020 Mar;119(3):747-751.

doi: 10.1016/j.jfma.2020.02.007. Epub 2020 Feb 26.

First case of Coronavirus Disease 2019 (COVID-19) pneumonia in Taiwan

Shao-Chung Cheng¹, Yuan-Chia Chang², Yu-Long Fan Chiang³, Yu-Chan Chien², Mingte Cheng⁴, Chin-Hua Yang⁵, Chia-Husn Huang⁶, Yuan-Nian Hsu⁷

Affiliations

¹ Division of Pulmonary Medicine, Department of Internal Medicine, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
² Department of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
³ Department of Internal Medicine, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
⁴ Department of Orthopedic Surgery, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
⁵ Department of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan; Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan; Department of Biomedical Engineering and Environmental Science, National Tsing Hua University, Hsinchu, Taiwan.
⁶ Division of Gastroenterology and Hepatology, Department of Internal Medicine, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan. Electronic address: 4719@mail.tygh.gov.tw.
⁷ Department of Family Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan. Electronic address: kingjen@mail.tygh.gov.tw.

PMID: 32113824
PMCID: PMC7127252
DOI: 10.1016/j.jfma.2020.02.007

Case Reports

First case of Coronavirus Disease 2019 (COVID-19) pneumonia in Taiwan

Shao-Chung Cheng et al. J Formos Med Assoc. 2020 Mar.

. 2020 Mar;119(3):747-751.

doi: 10.1016/j.jfma.2020.02.007. Epub 2020 Feb 26.

Authors

Shao-Chung Cheng¹, Yuan-Chia Chang², Yu-Long Fan Chiang³, Yu-Chan Chien², Mingte Cheng⁴, Chin-Hua Yang⁵, Chia-Husn Huang⁶, Yuan-Nian Hsu⁷

Affiliations

¹ Division of Pulmonary Medicine, Department of Internal Medicine, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
² Department of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
³ Department of Internal Medicine, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
⁴ Department of Orthopedic Surgery, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
⁵ Department of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan; Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan; Department of Biomedical Engineering and Environmental Science, National Tsing Hua University, Hsinchu, Taiwan.
⁶ Division of Gastroenterology and Hepatology, Department of Internal Medicine, Sinwu Branch, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan. Electronic address: 4719@mail.tygh.gov.tw.
⁷ Department of Family Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan. Electronic address: kingjen@mail.tygh.gov.tw.

PMID: 32113824
PMCID: PMC7127252
DOI: 10.1016/j.jfma.2020.02.007

Abstract

An outbreak of respiratory illness proved to be infected by a 2019 novel coronavirus, officially named Coronavirus Disease 2019 (COVID-19), was notified first in Wuhan, China, and has spread rapidly in China and to other parts of the world. Herein, we reported the first confirmed case of novel coronavirus pneumonia (NCP) imported from China in Taiwan. This case report revealed a natural course of NCP with self-recovery, which may be a good example in comparison with medical treatments.

Keywords: COVID-19; First case; Pneumonia; Taiwan.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest The authors have no conflicts of interest relevant to this article.

Figures

Fig. 1 — **Figure 1**
Vital sign, symptoms, and examination by the day of illness and day of hospitalization, January 11 to February 07, 2020.

Fig. 2 — **Figure 2**
Chest X-ray showed progression of prominent bilateral perihilar infiltration and ill-defined patchy opacities at bilateral lungs, which slowly resolved on the follow-up image. (a: January 20; b: Jan. 23; c: Jan. 27; d: February 04).

Fig. 3 — **Figure 3**
Chest CT in convalescent stage showed persistent multifocal GGOs with or without superimposed reticulation and mild fibrotic change at bilateral lungs, including peripheral subpleural regions of both lower lobes. Two small irregular opacities at the RUL and RML were probably partially resolved consolidations (arrows).

See this image and copyright information in PMC

Comment in

Author reply to Letters to the Editor "COVID-19 pneumonia in Taiwan".
Cheng SC, Fan Chiang YL, Huang CH, Hsu YN. Cheng SC, et al. J Formos Med Assoc. 2020 May;119(5):999. doi: 10.1016/j.jfma.2020.03.011. Epub 2020 Apr 2. J Formos Med Assoc. 2020. PMID: 32247592 Free PMC article. No abstract available.
COVID-19 pneumonia in Taiwan.
Joob B, Wiwanitkit V. Joob B, et al. J Formos Med Assoc. 2020 May;119(5):998. doi: 10.1016/j.jfma.2020.03.009. Epub 2020 Apr 2. J Formos Med Assoc. 2020. PMID: 32249108 Free PMC article. No abstract available.
Author reply to Letters to the Editor "CT chest findings in coronavirus disease (COVID-19)".
Chang YC, Yang CH, Chien YC, Hsu YN. Chang YC, et al. J Formos Med Assoc. 2020 May;119(5):1002-1003. doi: 10.1016/j.jfma.2020.03.012. Epub 2020 Apr 2. J Formos Med Assoc. 2020. PMID: 32249110 Free PMC article. No abstract available.
CT chest findings in coronavirus disease-19 (COVID-19).
Lal A, Mishra AK, Sahu KK. Lal A, et al. J Formos Med Assoc. 2020 May;119(5):1000-1001. doi: 10.1016/j.jfma.2020.03.010. Epub 2020 Apr 4. J Formos Med Assoc. 2020. PMID: 32265095 Free PMC article. No abstract available.
Risk of reactivation or reinfection of novel coronavirus (COVID-19).
Alizargar J. Alizargar J. J Formos Med Assoc. 2020 Jun;119(6):1123. doi: 10.1016/j.jfma.2020.04.013. Epub 2020 Apr 23. J Formos Med Assoc. 2020. PMID: 32340768 Free PMC article. No abstract available.
Saliva samples as an alternative for novel coronavirus (COVID-19) diagnosis.
Alizargar J, Etemadi Sh M, Aghamohammadi M, Hatefi S. Alizargar J, et al. J Formos Med Assoc. 2020 Jul;119(7):1234-1235. doi: 10.1016/j.jfma.2020.04.030. Epub 2020 May 1. J Formos Med Assoc. 2020. PMID: 32381379 Free PMC article. No abstract available.
The dilemmas of the classification of SARS-CoV-2 infection without clinical manifestations: Asymptomatic or presymptomatic.
Arteaga-Livias K, Pecho-Silva S, Panduro-Correa V, Rodríguez-Morales AJ. Arteaga-Livias K, et al. J Formos Med Assoc. 2020 Jul;119(7):1237-1238. doi: 10.1016/j.jfma.2020.05.009. Epub 2020 May 13. J Formos Med Assoc. 2020. PMID: 32405157 Free PMC article. No abstract available.
A severe-type COVID-19 case with prolonged virus shedding.
Liu Y, Chen X, Zou X, Luo H. Liu Y, et al. J Formos Med Assoc. 2020 Oct;119(10):1555-1557. doi: 10.1016/j.jfma.2020.05.004. Epub 2020 May 11. J Formos Med Assoc. 2020. PMID: 32414666 Free PMC article. No abstract available.
Antimicrobial resistance vs COVID-19: A bigger challenge in the post-pandemic era!
Haqqi A, Awan UA, Ahmed H, Afzal MS. Haqqi A, et al. J Formos Med Assoc. 2021 Jul;120(7):1537-1538. doi: 10.1016/j.jfma.2021.03.003. Epub 2021 Mar 14. J Formos Med Assoc. 2021. PMID: 33771414 Free PMC article. No abstract available.

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References

1. World Health Organization . World Health Organization; Geneva, Switzerland: 2020. Novel coronavirus situation report -28.https://www.who.int/docs/default-source/coronaviruse/situation-reports/2...
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1. Holshue M.L., DeBolt C., Lindquist S., Lofy K.H., Wiesman J., Bruce H. First case of 2019 novel coronavirus in the United States. N Englera J Med. 2020:1–9. doi: 10.1056/NEJMoa2001191. [Epub ahead of print] - DOI - PMC - PubMed
1. Wang D., Hu B., Hu C., Zhu F., Liu X., Zhang J. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. J Am Med Assoc. 2020:E1–E9. doi: 10.1001/jama.2020.1585. [Epub ahead of print] - DOI - PMC - PubMed
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[1] World Health Organization . World Health Organization; Geneva, Switzerland: 2020. Novel coronavirus situation report -28.https://www.who.int/docs/default-source/coronaviruse/situation-reports/2...

[2] World Health Organization . World Health Organization; Geneva, Switzerland: 2020. Novel coronavirus situation report -28.https://www.who.int/docs/default-source/coronaviruse/situation-reports/2...

[3] Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;S0140–6736(20):30183–30185. - PMC - PubMed

[4] Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;S0140–6736(20):30183–30185. - PMC - PubMed

[5] Holshue M.L., DeBolt C., Lindquist S., Lofy K.H., Wiesman J., Bruce H. First case of 2019 novel coronavirus in the United States. N Englera J Med. 2020:1–9. doi: 10.1056/NEJMoa2001191. [Epub ahead of print] - DOI - PMC - PubMed

[6] Holshue M.L., DeBolt C., Lindquist S., Lofy K.H., Wiesman J., Bruce H. First case of 2019 novel coronavirus in the United States. N Englera J Med. 2020:1–9. doi: 10.1056/NEJMoa2001191. [Epub ahead of print] - DOI - PMC - PubMed

[7] Wang D., Hu B., Hu C., Zhu F., Liu X., Zhang J. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. J Am Med Assoc. 2020:E1–E9. doi: 10.1001/jama.2020.1585. [Epub ahead of print] - DOI - PMC - PubMed

[8] Wang D., Hu B., Hu C., Zhu F., Liu X., Zhang J. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. J Am Med Assoc. 2020:E1–E9. doi: 10.1001/jama.2020.1585. [Epub ahead of print] - DOI - PMC - PubMed

[9] Arabi Y.M., Alothman A., Balkhy H.H., Al-Dawood A., AlJohani S., Al Harbi S. Treatment of Middle East respiratory syndrome with a combination of lopinavir-ritonavir and interferon-beta1b (MIRACLE trial): study protocol for a randomized controlled trial. Trials. 2018;19:81–93. - PMC - PubMed

[10] Arabi Y.M., Alothman A., Balkhy H.H., Al-Dawood A., AlJohani S., Al Harbi S. Treatment of Middle East respiratory syndrome with a combination of lopinavir-ritonavir and interferon-beta1b (MIRACLE trial): study protocol for a randomized controlled trial. Trials. 2018;19:81–93. - PMC - PubMed

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First case of Coronavirus Disease 2019 (COVID-19) pneumonia in Taiwan

Affiliations

First case of Coronavirus Disease 2019 (COVID-19) pneumonia in Taiwan

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Conflict of interest statement

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