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. 1977 Jan;27(1):30-3.

A defect of the alternative pathway of complement

J F Soothill, B A Harvey

A defect of the alternative pathway of complement

J F Soothill et al. Clin Exp Immunol. 1977 Jan.

Abstract

The sera of patients defective at opsonization for yeast phagocytosis fix haemolytic complement poorly following incubation with the alternative pathway complement activators, inulin and bacterial endotoxin. This suggests that the defect lies early in the alternative pathway of complement.

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References

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    1. Arch Dis Child. 1976 Feb;51(2):91-9 - PubMed
    1. N Engl J Med. 1970 Feb 12;282(7):354-8 - PubMed

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