Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review

Intracranial Infection and Inflammation

Majda M. Thurnher  1 , Pia C. Sundgren  2
Juerg Hodler  1 , Rahel A. Kubik-Huch  2 , Gustav K. von Schulthess  3
, editors.
In: Diseases of the Brain, Head and Neck, Spine 2020–2023: Diagnostic Imaging [Internet]. Cham (CH): Springer; 2020. Chapter 6.
IDKD Springer Series.
.
Affiliations
Free Books & Documents
Review

Intracranial Infection and Inflammation

Majda M. Thurnher et al.
Free Books & Documents

Excerpt

Central nervous system (CNS) infections carry high morbidity and mortality risks. The spectrum of infection includes: meningitis; ventriculitis; cerebritis/brain abscesses; subdural/epidural empyemas; and encephalitis.

The most common emerging inflammatory disorders that may affect the CNS are IgG-related disease, autoimmune encephalitis, neuromyelitis optica spectrum disorders (NMOSD), and Anti-GQ1b IgG antibody syndrome. Sarcoidosis and vasculitis may also affect the brain and spinal cord. Magnetic resonance imaging (MRI) is the method of choice in detection, evaluation, and follow-up of CNS infection and inflammation.

In this chapter, the imaging findings and diagnostic roadmaps of most common clinical challenges in infectious and inflammatory CNS disorders are discussed and illustrated.

PubMed Disclaimer

References

    1. Thurnher MM. Infections in immunocompromised patients. In: Barkhof F, Jäger R, Thurnher M, Rovira A, editors. Clinical neuroradiology. Berlin: Springer; 2019.
    1. Fukuoka H, Hirai T, Okuda T, et al. Comparison of the added value of contrast-enhanced 3D fluid-attenuated inversion recovery and magnetization-prepared rapid acquisition of gradient echo sequences in relation to conventional postcontrast T1-weighted images for the evaluation of leptomeningeal diseases at 3T. AJNR Am J Neuroradiol. 2010;31:868–73. - PMC - PubMed
    1. Toh CH, Wei KC, Chang CN, et al. Differentiation of pyogenic brain abscesses from necrotic glioblastomas with use of susceptibility-weighted imaging. AJNR Am J Neuroradiol. 2012;33:1534–8. - PMC - PubMed
    1. Antulov R, Dolic K, Fruehwald-Pallamar J, Miletic D, Thurnher MM. Differentiation of pyogenic and fungal brain abscesses with susceptibility-weighted MR sequences. Neuroradiology. 2014;56(11):937–45. - PubMed
    1. Thurnher MM. Bacterial infections. In: Barkhof F, Jäger R, Thurnher M, Rovira A, editors. Clinical neuroradiology. Berlin: Springer; 2019.

LinkOut - more resources