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Book

Diabetic Macular Edema

Chandni Duphare  1 , Koosh Desai  2 , Priyadarshi Gupta  3 , Bhupendra C. Patel  4
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Diabetic Macular Edema

Chandni Duphare et al.
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Excerpt

The retina is a thin layer of tissue in the posterior segment of the eye near the optic nerve. It contains a layer of photoreceptor cells, and receives focused light from the lens and converts the light into neural signals, because of this, the retina is a vital structure involved in vision and damage to it can have devastating consequences. The macula is the center of the retina and has the highest concentration of rods and cones (photoreceptors). Diabetes can lead to macular edema in a multifactorial manner. This is one of the leading causes of visual impairment in the United States. The first-line treatment usually involves anti-vascular endothelial growth factor (VEGF) therapy; however, new treatments are being developed.

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Conflict of interest statement

Disclosure: Chandni Duphare declares no relevant financial relationships with ineligible companies.

Disclosure: Koosh Desai declares no relevant financial relationships with ineligible companies.

Disclosure: Priyadarshi Gupta declares no relevant financial relationships with ineligible companies.

Disclosure: Bhupendra Patel declares no relevant financial relationships with ineligible companies.

References

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    1. Supuran CT. Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review. Expert Opin Ther Pat. 2019 Oct;29(10):761-767. - PubMed
    1. Bhagat N, Grigorian RA, Tutela A, Zarbin MA. Diabetic macular edema: pathogenesis and treatment. Surv Ophthalmol. 2009 Jan-Feb;54(1):1-32. - PubMed

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