Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Jan 17;8(2):247-253.
doi: 10.1002/ccr3.2572. eCollection 2020 Feb.

Dental management of scleroderma patients using pentoxifylline plus vitamin E with and without TheraBite® to reduce trismus: Two case reports and brief review of literature

Daniel N Reed  1 , David L Hall  1 , James H Cottle  1 , Katherine Frimenko  1 , Christina K Horton  1 , Farah Abu Sharkh  1 , Rachel Beckett  1 , Brandon Hernandez  1 , Hannah Mabe  1 , Shadee T Mansour  1 , Sebastian A Rodriguez  1 , Bradley Weprin  1 , Leigh E Yarborough  1
Affiliations
Case Reports

Dental management of scleroderma patients using pentoxifylline plus vitamin E with and without TheraBite® to reduce trismus: Two case reports and brief review of literature

Daniel N Reed et al. Clin Case Rep. .

Abstract

To provide evidence supporting the off label use of pentoxifylline and vitamin E especially by dentists with TheraByte to reduce trismus in scleroderma patients.

Keywords: Thera Bite®; VitE; pentoxifylline; scleroderma; trismus.

PubMed Disclaimer

Conflict of interest statement

There were no conflicts of interest or external funding sources to disclose.

Figures

Figure 1
Figure 1
TheraBite® Device
See this image and copyright information in PMC

References

    1. deSouza RBC, Macedo AR, Kuruma KA, Macedo PA. Pentoxifylline in association with vitamin E reduces cutaneous fibrosis in systemic sclerosis. Clin Rheumatol. 2009;28:1207‐1212. - PubMed
    1. Fischer DJ, Patton LL. Scleroderma: oral manifestations and treatment challenges. Spec Care Dent. 2000;20:240‐244. - PubMed
    1. Mayes MD, Lacey JV, Beebe‐Dimmer J, Gillespie BW. Prevalence, incidence, survival and disease characteristics of systemic sclerosis in a large US population. Arthritis & Rheum. 2003;48:2246‐2255. - PubMed
    1. Hachulla E, Launay D. Diagnosis and classification of systemic sclerosis. Clin Rev Allergy Immunol. 2011;40:78‐83. - PubMed
    1. Schumacher HR Jr, Kippel JH, Robinson DR, eds. Systemic sclerosis and localized scleroderma In: Primer on Rheumatic Diseases (9th edn). Atlanta, GA: Arthritis Foundation; 1988;111‐117.

Publication types

LinkOut - more resources