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Review
. 2020 Mar 2;15(Suppl 1):S3-S7.
doi: 10.1002/cld.843. eCollection 2020 Feb.

60 Days in Biliary Atresia: A Historical Dogma Challenged

Mary Elizabeth M Tessier  1 , Benjamin L Shneider  1
Affiliations
Review

60 Days in Biliary Atresia: A Historical Dogma Challenged

Mary Elizabeth M Tessier et al. Clin Liver Dis (Hoboken). .
No abstract available

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Figures

Figure 1
Figure 1
Outcome of Kasai hepatoportoenterostomy relative to age in days at the time of surgery. Enhanced outcomes were observed between 1971 and 1976 (lower panel) in those infants who were younger than 60 days at the time of surgery. Reproduced with permission from Neonatal Hepatitis and Biliary Atresia.3 Copyright 1977, U.S. Department of Health, Education, and Welfare.
Figure 2
Figure 2
Outcomes after the Kasai operation relative to age at surgery. Similar results were observed for infants undergoing surgery between 46 and 60 days of age relative to those between 61 and 75 days of age. Reproduced with permission from Pediatrics.7 Copyright 2009, American Academy of Pediatrics.
Figure 3
Figure 3
Timing of evaluation of BA. Age at presentation to the subspecialty center is correlated with the number of days under evaluation there. Infants who present at younger than 30 days have longer evaluation times, suggesting a perceived potential lack of urgency because of the presumption of a 60‐day time cutoff. Adapted with permission from Journal of Pediatric Gastroenterology and Nutrition.10 Copyright 2018, European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Figure 4
Figure 4
Liver Stiffness in Infants with Biliary Atresia. Transient elastography performed in infants prior to hepatoportoenterostomy at ages varying between 10 and 90 days of age (reproduced and modified with permission from the author and publisher).12 Superimposed upon the data are colored bands of ranges for normal values in older children (blue band, below) and findings of advanced liver disease (cirrhosis in pink and portal hypertension in yellow bands, respectively, above) described in children with BA who have undergone Kasai hepatoportoenterostomy.13, 14
See this image and copyright information in PMC

References

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