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Editorial
. 2020 Feb;9(1):106-108.
doi: 10.21037/hbsn.2019.08.11.

Independent regulation of tumorigenesis and fibrosis in non-alcoholic fatty liver disease

Rhys Gillman  1 , Lionel Hebbard  1
Affiliations
Editorial

Independent regulation of tumorigenesis and fibrosis in non-alcoholic fatty liver disease

Rhys Gillman et al. Hepatobiliary Surg Nutr. 2020 Feb.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Graphical model of the findings by Grohmann et al. (3) STAT-1 and STAT-3 can independently promote either NASH and fibrosis, or HCC respectively. NASH, non-alcoholic steatohepatitis; HCC, hepatocellular carcinoma.
See this image and copyright information in PMC

Comment on

  • Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
    Grohmann M, Wiede F, Dodd GT, Gurzov EN, Ooi GJ, Butt T, Rasmiena AA, Kaur S, Gulati T, Goh PK, Treloar AE, Archer S, Brown WA, Muller M, Watt MJ, Ohara O, McLean CA, Tiganis T. Grohmann M, et al. Cell. 2018 Nov 15;175(5):1289-1306.e20. doi: 10.1016/j.cell.2018.09.053. Epub 2018 Oct 25. Cell. 2018. PMID: 30454647 Free PMC article.

References

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    1. Grohmann M, Wiede F, Dodd GT, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell 2018;175:1289-306.e20. 10.1016/j.cell.2018.09.053 - DOI - PMC - PubMed
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