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Comment
. 2020 Mar 5;26(3):295-296.
doi: 10.1016/j.stem.2020.02.010.

A Specialized Few Among Many: Identification of a Novel Lung Epithelial Stem Cell Population

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Comment

A Specialized Few Among Many: Identification of a Novel Lung Epithelial Stem Cell Population

Christina E Barkauskas. Cell Stem Cell. .

Abstract

The landscape of lung epithelial stem cells is getting more nuanced. In this issue of Cell Stem Cell, Kathiriya et al. (2020) describe a novel distal airway epithelial cell population with high regenerative potential.

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Figures

Figure 1
Figure 1
The Complexity of the Epithelial Stem Cell Landscape in the Lung Is Increasing Subsets of stem cell populations, including the H2-K1high distal airway cells identified by Kathiriya et al. (2020), are becoming recognized as major contributors to alveolar epithelial regeneration. Stem cells are shown to be capable of either self-renewal (circular arrow) or differentiation (arched arrows pointing to a different cell type). The relative regenerative contribution of each stem cell population is depicted by the thickness of the corresponding arrows.

Comment on

References

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