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Review
. 2020 Apr;30(2):267-289.
doi: 10.1016/j.giec.2019.12.008. Epub 2020 Feb 13.

Transoral Incisionless Fundoplication

Kenneth J Chang  1 , Reginald Bell  2
Affiliations
Review

Transoral Incisionless Fundoplication

Kenneth J Chang et al. Gastrointest Endosc Clin N Am. 2020 Apr.

Abstract

GERD is a spectrum disorder, and treatment should be individualized to the patient's anatomic alterations. Trans-oral incisionless fundoplication (TIF 2.0) is an endoscopic procedure which reduces EGJ distensibility, thereby decreasing tLESRs, and also creates a 3-cm high pressure zone at the distal esophagus in the configuration of a flap valve. As it produces a partial fundoplication with a controlled valve diameter, gas can still escape from the stomach, minimizing the side-effect of gas-bloat. Herein we discuss the rationale, mechanism of action, patient selection, step-by-step procedure, safety and efficacy data, it's use with concomitant laparoscopic hernia repair, and future emerging indications.

Keywords: Esophagitis; Fundoplication; Gastroesophageal reflux; Hiatal hernia; Humans; Laparoscopy; Proton pump inhibitors; Treatment outcome reflux.

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Conflict of interest statement

Conflict-of-Interest Dr K.J. Chang has served as consultant for Apollo Endosurgery, Cook, Erbe, EndoGastric Solutions, Mauna Kea, Mederi, Medtronics, Olympus, Ovesco, and Pentax.