Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Feb 14:2020:5381012.
doi: 10.1155/2020/5381012. eCollection 2020.

The Prevalence of Single and Multiple Thyroid Nodules and Its Association with Metabolic Diseases in Chinese: A Cross-Sectional Study

Bing Zou  1 , Li Sun  1 , Xin Wang  2 , Zongtao Chen  1
Affiliations

The Prevalence of Single and Multiple Thyroid Nodules and Its Association with Metabolic Diseases in Chinese: A Cross-Sectional Study

Bing Zou et al. Int J Endocrinol. .

Abstract

Purpose: The present study aims to investigate the prevalence of single and multiple thyroid nodules and its association with metabolic diseases in subjects who participated in the heath examination in China.

Methods: This is a cross-sectional study. The participants who attend the physical examination at the Health Management Center of Southwest Hospital, Army Military Medical University, between January 2014 and December 2018, were included. Thyroid nodules were diagnosed by thyroid ultrasound. Multivariable logistic regression was used to investigate the association between metabolic diseases and nodular thyroid disease.

Results: A total of 9,146 subjects were included in this study; of them, 2,961 were diagnosed with thyroid nodules, with a prevalence of 32.4%. The prevalence in women was significantly higher than that in men (45.2% vs 26.0%; χ 2 = 339.56, P < 0.001), and the prevalence was gradually increased with age (Z = 20.05, P < 0.001), and the prevalence was gradually increased with age (.

Conclusions: The prevalence of thyroid nodules was relatively high. Age, female gender, and diabetes are positively associated with nodular thyroid disease. High LDL cholesterolemia is more likely to be associated with multiple thyroid sarcoidosis.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

References

    1. Guo A., Kaminoh Y., Forward T., Schwartz F. L., Jenkinson S. Fine needle aspiration of thyroid nodules using the bethesda system for reporting thyroid cytopathology: an institutional experience in a rural setting. International Journal of Endocrinology. 2017;2017:6. doi: 10.1155/2017/9601735.9601735 - DOI - PMC - PubMed
    1. Xu W., Huo L., Chen Z., et al. The relationship of TPOAb and TGAb with risk of thyroid nodules: a large epidemiological study. International Journal of Environmental Research and Public Health. 2017;14(7):p. 723. doi: 10.3390/ijerph14070723. - DOI - PMC - PubMed
    1. Uchino S., Noguchi S., Yamashita H., et al. Detection of asymptomatic differentiated thyroid carcinoma by neck ultrasonographic screening for familial nonmedullary thyroid carcinoma. World Journal of Surgery. 2004;28(11):1099–1102. doi: 10.1007/s00268-004-7676-x. - DOI - PubMed
    1. Skarpa V., Κousta E., Tertipi A., et al. Epidemiological characteristics of children with autoimmune thyroid disease. Hormones. 2011;10(3):207–214. doi: 10.14310/horm.2002.1310. - DOI - PubMed
    1. Yin J., Wang C., Shao Q., et al. Relationship between the prevalence of thyroid nodules and metabolic syndrome in the iodine-adequate area of Hangzhou, China: a cross-sectional and cohort study. International Journal of Endocrinology. 2014;2014:7. doi: 10.1155/2014/675796.675796 - DOI - PMC - PubMed

LinkOut - more resources