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Case Reports
. 2020 Feb 19:2020:8474905.
doi: 10.1155/2020/8474905. eCollection 2020.

Leiomyoma of the Cheek

Ricardo Roberto de Souza Fonseca  1 , Mário Augusto Ramos Junior  2 , Douglas Baruchi  3 , Tabata Resque Beckmann Carvalho  4 , Andresa Borges Soares  3 , Silvio Augusto Fernandes de Menezes  5 , João de Jesus Viana Pinheiro  6 , Jorge Nazareno Ferreira Fadul  2
Affiliations
Case Reports

Leiomyoma of the Cheek

Ricardo Roberto de Souza Fonseca et al. Case Rep Pathol. .

Abstract

Leiomyomas are rare benign tumors that grow in the tunica media of smooth muscle cells. Leiomyomas occur most frequently in the uterus or gastrointestinal tract and only very rarely in the area of the cheek. This study reports on a rare case of a leiomyoma in the cheek of a 43-year-old woman, who presented with a well-circumscribed, asymptomatic, mobile swelling in the right cheek. This swelling was slightly purplish in color and measured approximately 4 cm × 3 cm. Surgical excision was the treatment of choice, and the diagnosis was based on histopathological and immunohistochemical stains, which were positive for actin and desmin and negative for AE1/AE3, CD34, and S100. The patient's follow-up, two years later, showed no recurrence, and she has been asymptomatic since the surgery.

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Conflict of interest statement

The authors declare having no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1
Figure 1
(a, b) Clinical aspect of the lesion, showing the large size of the growth.
Figure 2
Figure 2
(a) Axial plane and (b) coronal plane, showing the lesion as a dense mass of soft tissue with defined contours and foci of calcification.
Figure 3
Figure 3
Macroscopic aspect of the leiomyoma.
Figure 4
Figure 4
(a) Proliferation of spindle cells arranged in interlocking bundles in a monotonous pattern of fascicles (hematoxylin and eosin stain; original magnification 20x). (b) Immunohistochemical stain showing strong positivity for desmin (original magnification 20x).
Figure 5
Figure 5
(a) Axial plane and (b) coronal plane, showing the postoperative aspects of the affected region.
Figure 6
Figure 6
Two-year follow-up with no signs of recurrence.
See this image and copyright information in PMC

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