Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Feb;11(1):8-14.
doi: 10.24171/j.phrp.2020.11.1.03.

Early Epidemiological and Clinical Characteristics of 28 Cases of Coronavirus Disease in South Korea

Early Epidemiological and Clinical Characteristics of 28 Cases of Coronavirus Disease in South Korea

COVID-19 National Emergency Response Center, Epidemiology and Case Management Team, Korea Centers for Disease Control and Prevention. Osong Public Health Res Perspect. 2020 Feb.

Abstract

Objectives: The first confirmed case of coronavirus disease 2019 (COVID-19) in South Korea was reported in January 2020, with 28 confirmed cases reported as of February 14th, 2020. The epidemiological and clinical characteristics of all 28 cases were analyzed in response to this disease.

Methods: The epidemiological characteristics and early clinical features of the 28 patients from Korea with confirmed COVID-19 were analyzed using COVID-19 reporting and surveillance data and the epidemiological investigation reports prepared by the rapid response team.

Results: There were 16 patients that entered Korea from foreign countries: Wuhan, China (11 patients), Zhuhai, China, (1 patient), Singapore (2 patients), Japan (1 patient), and Thailand (1 patient). The early symptoms were fever, sore throat, cough or sputum production, chills, and muscle ache. Three patients were asymptomatic, however, 18 developed pneumonia. Of the 28 cases, 16 were index cases imported from abroad, with 10 cases of secondary infection originating in Korea, and the route of transmission still under investigation for 2 patients. The 10 patients with secondary infection were infected from contact with family members or acquaintances of primary patients, and the suspected sites of transmission were mostly at home.

Conclusion: COVID-19 in Korea was spread by 16 infected individuals traveling from other countries, leading to second-generation cases. The initial symptoms were mostly minor, but the disease was infectious at this stage, resulting from close contact, particularly at home. Establishing an early detection strategy for COVID-19 is crucial for managing the transmission of the disease.

Keywords: COVID-19; SARS-CoV-2; epidemiologic study.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
COVID-19 epidemic curve (onset of signs and symptoms). COVID-19 = coronavirus disease 2019.
Figure 2
Figure 2
Transmission dynamics in cases of coronavirus disease.

References

    1. World Health Organization [Internet] Coronavirus disease (COVID-19): Situation reports. Geneva (Switzerland): World Health Organization; 2020. [cited 2020 Feb 17]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situatio....
    1. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet. 2020;395(10223):507–13. doi: 10.1016/S0140-6736(20)30211-7. - DOI - PMC - PubMed
    1. Korea Centers for Disease Control and Prevention [Internet] COVID-19: Health alerts, the fastest updates. Cheongju (Korea): Korea Centers for Disease Control and Prevention; 2020. [cited 2020 Feb 14]. Available from: http://ncov.mohw.go.kr/tcmBoardList.do?brdId=&brdGubun=&dataGubun=&ncvCo...
    1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed
    1. Li Q, Guan X, Wu P, et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. New Engl J Med. 2020 doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29. [Epub ahead of print] - DOI - PMC - PubMed