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. 2020 May;47(5):329-331.
doi: 10.1097/OLQ.0000000000001158.

No Pathogen-Specific Sign or Symptom Predicts the Etiology of Monomicrobial Nongonococcal Urethritis in Men

Stephen J Jordan, Evelyn Toh  1 , James A Williams  2 , Lora J Fortenberry  1 , Michelle LaPradd  3 , John D Ryan  1 , David E Nelson  1 , Teresa A Batteiger  2
Affiliations

No Pathogen-Specific Sign or Symptom Predicts the Etiology of Monomicrobial Nongonococcal Urethritis in Men

Stephen J Jordan et al. Sex Transm Dis. 2020 May.

Abstract

Identifying pathogen-specific signs or symptoms of nongonococcal urethritis could improve syndromic management accuracy. We evaluated nongonococcal urethritis signs and symptoms in 220 men with single-pathogen infections (Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, or Ureaplasma urealyticum) or idiopathic urethritis. No individual sign or symptom accurately predicted the infectious etiology.

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Conflict of interest statement

Statement of Conflict of Interest: The authors have no conflicts to disclose.

Figures

Figure 1.
Figure 1.. Percent NGU cases with urethritis symptoms and signs, stratified by pathogen and IU.
(A) Frequency of NGU symptoms by group. (B) Frequency of NGU signs by group. (C) Frequency of discharge amount and color by group. Significance was evaluated by Chi-square or Fisher’s exact test. Significance set at P<0.05. No significant differences were observed. Symptoms with N≤5 were excluded.
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References

    1. Martin D Urethritis in Males In: Holmes KKSP, Stamm WE, ed. Sexually Transmitted Diseases. 4th ed New York: McGraw-Hill; 2008:1107–26.
    1. Wetmore CM, Manhart LE, Golden MR. Idiopathic urethritis in young men in the United States: prevalence and comparison to infections with known sexually transmitted pathogens. J Adolesc Health. 2009;45(5):463–72. - PMC - PubMed
    1. Workowski KA, Bolan GA, Papp JR. Sexually transmitted diseases treatment guidelines, 2015; 2015:1–137. - PMC - PubMed
    1. Papp JR, Schachter J, Gaydos C, Van Der Pol B. Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae--2014. MMWR. 2014;63(RR-02):1–19. - PMC - PubMed
    1. Sena AC, Lensing S, Rompalo A, et al. Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis infections in men with nongonococcal urethritis: predictors and persistence after therapy. J Infect Dis. 2012;206(3):357–65. - PMC - PubMed

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