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Case Reports
. 2020 Mar 8;13(3):e233798.
doi: 10.1136/bcr-2019-233798.

Demyelinating steroid-responsive neurobrucellosis

Fateen Ata  1 , Zohaib Yousaf  2 , Mohammad Khalid Sharif  3 , Ahmed Abdallah  1
Affiliations
Case Reports

Demyelinating steroid-responsive neurobrucellosis

Fateen Ata et al. BMJ Case Rep. .

Abstract

Young man with acute onset nausea, vomiting, joint pain, abdominal pain, fever and weight loss was found to have gait ataxia and positive B rucella titres. He deteriorated despite appropriate antibiotics and developed confusion and disorientation. Lumbar puncture revealed lymphocytosis with high protein and low glucose. MRI showed diffuse demyelination. Pulse steroids resulted in rapid clinical, biochemical and radiological recovery.

Keywords: disease and health outcomes; exposures; infection (neurology); medical management; meningitis.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Pretreatment. (A) Brainstem enhancement. (B) Trigeminal enhancement. (C) Posterior parietal periventricular demyelination. (D, E) Splenium of corpus callosum demyelination. (F) Fourth ventricle demyelination.
Figure 2
Figure 2
Post-treatment. (A, B) Splenium of corpus callosum. (C) Resolved fourth ventricle demyelination. (D) Brainstem.
See this image and copyright information in PMC

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