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Editorial
. 2019 Dec;14(4):378-383.
doi: 10.26574/maedica.2019.14.4.378.

Atherosclerosis Burden and Therapeutic Challenges Regarding Acute Coronary Syndromes in Chronic Kidney Disease Patients

Madalina Ioana Moisi  1 , Cosmin Vesa  1 , Larisa Pantea Rosan  1 , Otilia Tica  1 , Adriana Ardelean  1 , Dana Zaha  1 , Ovidiu Burta  1 , Mircea Ioachim Popescu  1
Affiliations
Editorial

Atherosclerosis Burden and Therapeutic Challenges Regarding Acute Coronary Syndromes in Chronic Kidney Disease Patients

Madalina Ioana Moisi et al. Maedica (Bucur). 2019 Dec.

Abstract

The major cause of death in patients with chronic kidney disease is represented by cardiovascular events. Atherosclerosis is usually initiated by the association of traditional and non-traditional risk factors, and the acute thrombotic complications are more frequent in subjects with reduced glomerular filtration rate. The diagnosis of acute coronary syndromes is challenging due to the increased values of cardiac necrosis enzymes correlated with reduced renal function.

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Figures

TABLE 1.
TABLE 1.
Differences between atherosclerosis and arteriosclerosis and pathophysiological aspects of the two lesions
FIGURE 1.
FIGURE 1.
Traditional and non-traditional risk factors involved in atherosclerotic process in subjects with CKD disease. There are two particular complications of the accelerated atherosclerosis consisting in the white thrombus, which is mainly formed by platelets and the red thrombus, rich in fibrin. HBP= High blood pressure; CVD= cardiovascular disease.
See this image and copyright information in PMC

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