Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Feb 29:31:101149.
doi: 10.1016/j.eucr.2020.101149. eCollection 2020 Jul.

Pan-urethral condylomata acuminata - A primary treatment recommendation based on our experience

Brennan Timm  1   2 , Thea Connor  2 , Peter Liodakis  1   2 , Jyotsna Jayarajan  1   2
Affiliations
Case Reports

Pan-urethral condylomata acuminata - A primary treatment recommendation based on our experience

Brennan Timm et al. Urol Case Rep. .

Abstract

We present a case of a 28 year old man presenting with obstructive urinary tract symptoms and cystoscopic findings of pan-urethral, occlusive condylomata acuminata (urethral genital warts). We describe the in rooms administration process of 5-fluorouracil over an 8 week period with follow up cystoscopy results. Urine flow rates improved early in the treatment course from a maximum flow of 7ml/s to 19ml/s and a post void residual improvement from 311ml to 160ml. Significant volume reduction of the warts was achieved allowing for limited treatment with cold excision to minimise urethral stricture risk in a young man.

Keywords: Condyloma acuminatum; Condylomata acuminata; Urethral warts.

PubMed Disclaimer

Conflict of interest statement

We declare no conflicts of interest and no funding sources in the presentation of these works.

Figures

Fig. 1
Fig. 1
Cystoscopy findings pre-treatment and post treatment with urethral 5FU and focal surgical treatment.
Fig. 2
Fig. 2
H&E 100x magnification, features suggestive of condylomata acuminata - papillomatosis, surface hyperkeratosis and koilocytic change.
Fig. 3
Fig. 3
Equipment set up and administration preparation by our practise nurse. NB – Importance of all plastic utensils to avoid metal ion binding and making the 5FU less effective.
See this image and copyright information in PMC

References

    1. Wein A.J., Benson G.S. Treatment of urethral condyloma acuminatum with 5-fluorouracil cream. Urology. 1977;9(4):413–415. - PubMed
    1. Gammon D.C., Reed K.A., Patel M., Balaji K.C. Intraurethral fluorouracil and lidocaine for intraurethral condyloma acuminata. Am J Health Syst Pharm. 2008;65(19):1830–1833. - PubMed
    1. Dretler SP, Klein LA. The eradication of intraurethral condyloma acuminata with 5 per cent 5-fluorouracil cream. J Urol.113(2):195-198. - PubMed
    1. Wallin J. 5-Fluorouracil in the treatment of penile and urethral condylomata acuminata. Br J Vener Dis. 1977;53(4):240–243. - PMC - PubMed
    1. Florin H.J., Snoeck R., Van Cleynenbreugel B., Albersen M. Treatment of intraurethral condylomata acuminata with surgery and cidofovir instillations in two immunocompromised patients and review of the literature. Antivir Res. 2018;158:238–243. - PubMed

Publication types

LinkOut - more resources