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Sepsis and septic shock in newborns causes mortality and morbidity depending on the organism and primary site. ECMO provides cardiorespiratory support to allow adequate organ perfusion during the time for antibiotics and source control surgery (if needed) to occur. ECMO mode and cannulation site vary depending on support required and local preference. Earlier and more aggressive use of ECMO can improve survival.
Group IC, Brocklehurst P, Farrell B, King A, Juszczak E, Darlow B, et al. Treatment of neonatal sepsis with intravenous immune globulin. N Engl J Med. (2011) 365:1201–11. 10.1056/NEJMoa1100441
-
DOI
-
PubMed
Lukacs SL, Schrag SJ. Clinical sepsis in neonates and young infants, United States, 1988-2006. J Pediatr. (2012) 160:960–5 e961. 10.1016/j.jpeds.2011.12.023
-
DOI
-
PubMed
Wynn JL, Wong HR. Pathophysiology and treatment of septic shock in neonates. Clin Perinatol. (2010) 37:439–79. 10.1016/j.clp.2010.04.002
-
DOI
-
PMC
-
PubMed
Stoll BJ, Hansen NI, Sanchez PJ, Faix RG, Poindexter BB, Van Meurs KP, et al. . Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continues. Pediatrics. (2011) 127:817–26. 10.1542/peds.2010-2217
-
DOI
-
PMC
-
PubMed