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Review
. 2020 Feb 20:7:5.
doi: 10.3389/fvets.2020.00005. eCollection 2020.

A Mini-Review on the Epidemiology of Canine Parvovirus in China

Shanshan Qi  1 , Jianjun Zhao  1 , Donghua Guo  1 , Dongbo Sun  1
Affiliations
Review

A Mini-Review on the Epidemiology of Canine Parvovirus in China

Shanshan Qi et al. Front Vet Sci. .

Abstract

Canine viral diarrhea is a severe disease in dogs worldwide. The role of canine parvovirus (CPV) in canine viral diarrhea is a common health problem in dogs, attracting major concern from veterinarians and dog owners across China. In this mini-review, we summarize the CPV epidemiology in China, including its origin, prevalence, coinfection, and the genetic evolution of the virus. The review reveals the correlation between CPV-2 infection and seasonality, a dog's age/gender/breed/vaccination; that CPV-2 is the main causative agent of canine diarrhea in Northeast China and that coinfection with other pathogens is a common occurrence; the predominant CPV epidemic strains were the new CPV-2a, and CPV-2c has shown significant growth trends since 2010. This mini-review will provide valuable information for CPV infections across China and other countries.

Keywords: canine parvovirus; coinfection; epidemiology; phylogenetic analysis; prevalence.

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Figures

Figure 1
Figure 1
(A) Temporal distribution analysis of the morbidity of canine parvovirus (CPV) in China. (B) Temporal distribution analysis of the mortality of CPV in China. (C) Temporal distribution analysis of antibody levels of CPV in China.
Figure 2
Figure 2
Seasonal correlation analysis of canine parvovirus (CPV) infections in China.
Figure 3
Figure 3
Monthly correlation analysis of canine parvovirus (CPV) infections in China.
Figure 4
Figure 4
Correlation between a dog's age and canine parvovirus (CPV) infection in China.
Figure 5
Figure 5
Correlation between a dog's gender and canine parvovirus (CPV) infection in China. ***P < 0.05.
Figure 6
Figure 6
Correlation between dog breeds and canine parvovirus (CPV) infection in China.
Figure 7
Figure 7
Correlation between dog vaccinations and canine parvovirus (CPV) infection in China. **P < 0.05.
Figure 8
Figure 8
(A) Coinfection analysis of CPV with multiple pathogens. (B) The coinfection rate of CPV with other enteric viruses or bacteria. The data were cited from previously published papers (, –71) in our lab.
Figure 9
Figure 9
(A) Temporal distribution analysis of canine parvovirus (CPV) subtypes in China. (B) Geographical distribution analysis of CPV subtypes in China.
Figure 10
Figure 10
Phylogenetic analysis of canine parvovirus (CPV) strains based on VP2 gene sequences.
See this image and copyright information in PMC

References

    1. Kelly WR. An enteric disease of dogs reselmbing feline panleucopaenia. Aust Vet J. (1978) 54:593. 10.1111/j.1751-0813.1978.tb02426.x - DOI - PubMed
    1. Appel MJ, Cooper BJ, Greisen H, Scott F, Carmichael LE. Canine viral enteritis. I. Status report on corona- and parvo-like viral enteritides. Cornell Vet. (1979) 69:123–133. - PubMed
    1. Decaro N, Buonavoglia C. Canine parvovirus-a review of epidemiological and diagnostic aspects, with emphasis on type 2c. Vet Microbiol. (2012) 155:1–12. 10.1016/j.vetmic.2011.09.007 - DOI - PMC - PubMed
    1. Yi L, Tong M, Cheng Y, Song W, Cheng S. Phylogenetic analysis of canine parvovirus VP2 gene in China. Transbound Emerg Dis. (2016) 63:e262–9. 10.1111/tbed.12268 - DOI - PubMed
    1. Zhou P, Zeng W, Zhang X, Li S. The genetic evolution of canine parvovirus-A new perspective. PLoS ONE. (2017) 12:e0175035. 10.1371/journal.pone.0175035. - DOI - PMC - PubMed

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