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. 2020 Mar 9;30(5):R219-R221.
doi: 10.1016/j.cub.2020.01.057.

Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed

Matthias Eikermann  1 , Oluwaseun Akeju  2 , Nancy L Chamberlin  3
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Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed

Matthias Eikermann et al. Curr Biol. .
Free article

Abstract

Acute activation of genetically defined sleep-promoting neurons in the preoptic hypothalamus does not facilitate anesthesia. This finding supports the notion that a mechanistic overlap between sleep and anesthesia does not explain the anesthetized brain.

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