Autophagy Suppresses Breast Cancer Metastasis
- PMID: 32155434
- DOI: 10.1016/j.devcel.2020.02.005
Autophagy Suppresses Breast Cancer Metastasis
Abstract
Cancer cells need to acquire specific molecular traits in order to spread to distant organs. In this issue of Developmental Cell, Marsh et al. show that autophagy restricts the outgrowth of breast cancer metastases in contrast to its impact on primary tumor progression.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
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Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.Dev Cell. 2020 Mar 9;52(5):591-604.e6. doi: 10.1016/j.devcel.2020.01.025. Epub 2020 Feb 20. Dev Cell. 2020. PMID: 32084360 Free PMC article.
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