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Review
. 2020 Mar 6;12(3):598.
doi: 10.3390/polym12030598.

Progress in Polymeric Nano-Medicines for Theranostic Cancer Treatment

Affiliations
Review

Progress in Polymeric Nano-Medicines for Theranostic Cancer Treatment

Imran Ali et al. Polymers (Basel). .

Abstract

Cancer is a life-threatening disease killing millions of people globally. Among various medical treatments, nano-medicines are gaining importance continuously. Many nanocarriers have been developed for treatment, but polymerically-based ones are acquiring importance due to their targeting capabilities, biodegradability, biocompatibility, capacity for drug loading and long blood circulation time. The present article describes progress in polymeric nano-medicines for theranostic cancer treatment, which includes cancer diagnosis and treatment in a single dosage form. The article covers the applications of natural and synthetic polymers in cancer diagnosis and treatment. Efforts were also made to discuss the merits and demerits of such polymers; the status of approved nano-medicines; and future perspectives.

Keywords: approved nano-medicines; future perspectives; merits and demerits; polymeric nanoparticles; theranostic cancer treatment.

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Conflict of interest statement

There is no conflict of interest for this manuscript.

Figures

Figure 1
Figure 1
The schematic representation of polymeric nano-partcles (NPs) theranostic approach.
Figure 2
Figure 2
The different types of polymeric NPs as carriers for drugs delivery.
Figure 3
Figure 3
The timeline of the development of polymeric NPs based drugs for cancer treatment [79].
Figure 4
Figure 4
Numbers of the patents on the different types of NP-based drugs deliver systems.

References

    1. Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 2018;68:394–424. doi: 10.3322/caac.21492. - DOI - PubMed
    1. Aboul-Enein H.Y., Ali I. Determination of tadalafil in pharmaceutical preparation by HPLC using monolithic silica column. Talanta. 2004;65:276–280. doi: 10.1016/j.talanta.2004.06.012. - DOI - PubMed
    1. Ali I., Gaitonde V.D., Aboul-Enein H.Y., Hussain A. Chiral separation of β-adrenergic blockers on cellucoat column by HPLC. Talanta. 2009;78:458–463. doi: 10.1016/j.talanta.2008.11.043. - DOI - PubMed
    1. Ali I., Saleem K., Hussain I., Gaitonde V.D., Aboul-Enein H.Y. Polysaccharides chiral stationary phases in liquid chromatography. Sep. Purif. Rev. 2009;38:97–147. doi: 10.1080/15422110802589916. - DOI
    1. Ali I., Gupta V.K., Aboul-Enein H.Y., Prashant S., Bhavtosh S. Role of racemization in optically active drug development. Chirality. 2007;19:453–463. doi: 10.1002/chir.20397. - DOI - PubMed

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