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Case Reports
. 2020 Mar-Apr;95(2):255-256.
doi: 10.1016/j.abd.2019.01.012. Epub 2020 Jan 31.

Bullous congenital diffuse cutaneous mastocytosis

Julia Marcon Cardoso  1 , Camila Angelico S Cabral  2 , Rute Facchini Lellis  3 , Flavia Naranjo Ravelli  4
Affiliations
Case Reports

Bullous congenital diffuse cutaneous mastocytosis

Julia Marcon Cardoso et al. An Bras Dermatol. 2020 Mar-Apr.
No abstract available

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Figures

Figure 1
Figure 1
Erythematous plaques present at birth.
Figure 2
Figure 2
Erythematous brownish plaques on lower limb, topped by blisters at different stages of development (stray blisters, flaccid blisters and exulcerations).
Figure 3
Figure 3
Left: numerous mast cells arranged diffusely in the dermis stained by Hematoxylin & eosin. Right: the CD117 immunohistochemical reaction (c-kit) is diffusely positive in mast cells.
See this image and copyright information in PMC

References

    1. Lee H.J., Jang M.J., Bae E.Y., Han S.B., Jeong D.C., Kang J.H. Bullous cutaneous mastocytosis, a rarely reported disease in Asian children. Asian Pac J Allergy Immunol. 2014;32:354–357. - PubMed
    1. Valent P., Akin C., Metcalfe D.D. Mastocytosis: 2016 update WHO classification and novel emerging treatment concepts. Blood. 2017;129:1420–1427. - PMC - PubMed
    1. Koga H., Kokubo T., Akaishi M., Iida K., Korematsu S. Neonatal onset diffuse cutaneous mastocytosis: a case report and review of the literature. Pediatr Dermatol. 2011;28:542–546. - PubMed
    1. Castells M., Metcalfe D., Escribano L. Guidelines for the diagnosis and treatment of cutaneous mastocytosis in children. Am J Clin Dermatol. 2011;12:259–270. - PMC - PubMed
    1. Murphy M., Walsh D., Drumm B., Watson R. Bullous Mastocytosis: a fatal outcome. Pediatr Dermatol. 1999;16:452–455. - PubMed

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