Controversial Topics in Total Knee Arthroplasty: A Five-Year Update (Part 2)
- PMID: 32159069
- PMCID: PMC7028789
- DOI: 10.5435/JAAOSGlobal-D-19-00048
Controversial Topics in Total Knee Arthroplasty: A Five-Year Update (Part 2)
Abstract
This review article examines updates to the literature during the past 5 years on numerous topics which were felt to have ongoing controversy. These topics include venous thromboprophylaxis, tranexamic acid usage, tourniquet usage, and wound closure techniques.
Methods: For each individual topic, a literature search was conducted on several databases with emphasis on studies that were published in the past 5 years. Preference was given to meta-analyses and randomized controlled trials.
Results: Tranexamic acid is a safe and effective treatment modality, and consideration should be given to use multiple doses and combine different modes of administration. Certain treatment modalities (skin sutures, limited or no tourniquet usage) can cause greater patient satisfaction at a cost of longer operating times. Postoperative anticoagulation is still a very controversial topic. There is however some evidence suggesting prolonging anticoagulation to 35 days postoperative.
Conclusions: By analyzing the results of the aforementioned studies, surgeons can implement the most up-to-date evidence-based care when doing total knee arthroplasty surgery. However, many of these selected topics continue to have a component of ongoing controversy with no definitive conclusions developed in recent literature.
Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons.
Conflict of interest statement
Neither of the following authors nor any immediate family member has received anything of value from or has stock or stock options held in a commercial company or institution related directly or indirectly to the subject of this article: Dr. van der Merwe and Dr. Mastel.
Figures
Similar articles
-
Comparison of pharmacologic prophylaxis in prevention of venous thromboembolism following total knee arthroplasty.Knee. 2019 Mar;26(2):451-458. doi: 10.1016/j.knee.2019.01.004. Epub 2019 Jan 27. Knee. 2019. PMID: 30700390
-
Use of a Tourniquet in Total Knee Arthroplasty Causes a Paradoxical Increase in Total Blood Loss.J Bone Joint Surg Am. 2017 Aug 16;99(16):1331-1336. doi: 10.2106/JBJS.16.00750. J Bone Joint Surg Am. 2017. PMID: 28816892
-
Topical Tranexamic Acid Is Effective in Cementless Total Knee Arthroplasty.Orthop Clin North Am. 2020 Jan;51(1):7-11. doi: 10.1016/j.ocl.2019.08.002. Epub 2019 Oct 17. Orthop Clin North Am. 2020. PMID: 31739881 Review.
-
Controversial Topics in Total Knee Arthroplasty: A 5-Year Update (Part 1).J Am Acad Orthop Surg Glob Res Rev. 2020 Jan;4(1):e1900047. doi: 10.5435/JAAOSGlobal-D-19-00047. J Am Acad Orthop Surg Glob Res Rev. 2020. PMID: 32672726 Free PMC article. Review.
-
Intra-articular versus intravenous tranexamic acid application in total knee arthroplasty: a meta-analysis of randomized controlled trials.Arch Orthop Trauma Surg. 2017 Jul;137(7):997-1009. doi: 10.1007/s00402-017-2683-1. Epub 2017 Apr 4. Arch Orthop Trauma Surg. 2017. PMID: 28378211 Review.
Cited by
-
Significant increase in quantity and quality of knee arthroplasty related research in KSSTA over the past 15 years.Knee Surg Sports Traumatol Arthrosc. 2022 Apr;30(4):1239-1249. doi: 10.1007/s00167-021-06555-2. Epub 2021 Apr 10. Knee Surg Sports Traumatol Arthrosc. 2022. PMID: 33837808 Free PMC article.
References
-
- Fillingham YA, Kayupov E, Plummer DR, Moric M, Gerlinger TL, Della Valle CJ: The James A. Rand Young Investigator's Award: A randomized controlled trial of oral and intravenous tranexamic acid in total knee arthroplasty: The same efficacy at lower cost? J Arthroplasty 2016;31:26-30. - PubMed
-
- Stowers MDJ, Aoina J, Vane A, Poutawera V, Hill AG, Munro JT: Tranexamic acid in knee surgery study—a multicentered, randomized, controlled trial. J Arthroplasty 2017;32:3379-84. - PubMed
-
- Wang D, Wang HY, Luo ZY, et al. : Blood-conserving efficacy of multiple doses of oral tranexamic acid associated with an enhanced-recovery programme in primary total knee arthroplasty: A randomized controlled trial. Bone Joint J 2018;100-b:1025-32. - PubMed
-
- Lei Y, Xie J, Xu B, Xie X, Huang Q, Pei F: The efficacy and safety of multiple-dose intravenous tranexamic acid on blood loss following total knee arthroplasty: A randomized controlled trial. Int Orthop 2017;41:2053-9. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous