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Comment
. 2020 Apr;24(4):265-266.
doi: 10.1016/j.tics.2020.02.002. Epub 2020 Feb 24.

Unravelling the Neurobiology of Interoceptive Inference

Micah Allen  1
Affiliations
Comment

Unravelling the Neurobiology of Interoceptive Inference

Micah Allen. Trends Cogn Sci. 2020 Apr.

Abstract

What is the function of the insular cortex? Two recent studies (by Gehrlach et al. and Livneh et al.) offer new insight into how this enigmatic brain region integrates interoception and exteroception in the service of emotion. The findings provide much needed causal evidence for the nascent theory of interoceptive inference.

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  • Aversive state processing in the posterior insular cortex.
    Gehrlach DA, Dolensek N, Klein AS, Roy Chowdhury R, Matthys A, Junghänel M, Gaitanos TN, Podgornik A, Black TD, Reddy Vaka N, Conzelmann KK, Gogolla N. Gehrlach DA, et al. Nat Neurosci. 2019 Sep;22(9):1424-1437. doi: 10.1038/s41593-019-0469-1. Epub 2019 Aug 27. Nat Neurosci. 2019. PMID: 31455886
  • Estimation of Current and Future Physiological States in Insular Cortex.
    Livneh Y, Sugden AU, Madara JC, Essner RA, Flores VI, Sugden LA, Resch JM, Lowell BB, Andermann ML. Livneh Y, et al. Neuron. 2020 Mar 18;105(6):1094-1111.e10. doi: 10.1016/j.neuron.2019.12.027. Epub 2020 Jan 16. Neuron. 2020. PMID: 31955944 Free PMC article.

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