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Review
. 2019 Nov 27;4(1):bpz014.
doi: 10.1093/biomethods/bpz014. eCollection 2019.

Digging deeper into volatile organic compounds associated with cancer

Sajjad Janfaza  1   2 , Babak Khorsand  3 , Maryam Nikkhah  2 , Javad Zahiri  4
Affiliations
Review

Digging deeper into volatile organic compounds associated with cancer

Sajjad Janfaza et al. Biol Methods Protoc. .

Abstract

Volatile organic compounds (VOCs), produced and emitted through the metabolism of cancer cells or the body's immune system, are considered novel cancer biomarkers for diagnostic purposes. Of late, a large number of work has been done to find a relationship between VOCs' signature of body and cancer. Cancer-related VOCs can be used to detect several types of cancers at the earlier stages which in turn provide a significantly higher chance of survival. Here we aim to provide an updated picture of cancer-related VOCs based on recent findings in this field focusing on cancer odor database.

Keywords: aldehydes; cancer diagnosis; cancer odor; lung cancer; volatile organic compounds.

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Figures

Figure 1:
Figure 1:
Frequency of VOCs detected in various types of biological matrices.
Figure 2:
Figure 2:
The network representations of cancer-related VOCs (shown by their PubChem ID) and cancer types obtained from analyzing the COD database.
Figure 3:
Figure 3:
VOCs related to four or more than four types of cancer. The number of different types of cancer in which the VOCs are contributed is indicated.
See this image and copyright information in PMC

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