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Review
. 2020 Jun;92(6):577-583.
doi: 10.1002/jmv.25757. Epub 2020 Mar 23.

COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis

Long-Quan Li  1   2   3 , Tian Huang  1   2   3 , Yong-Qing Wang  4 , Zheng-Ping Wang  5 , Yuan Liang  1   2   3 , Tao-Bi Huang  1   2   3 , Hui-Yun Zhang  1   2   3 , Weiming Sun  6 , Yuping Wang  2   3
Affiliations
Review

COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis

Long-Quan Li et al. J Med Virol. 2020 Jun.

Abstract

The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help. The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate and fatality rate with a single-arm meta-analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C-reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single-arm meta-analysis showed that the male took a larger percentage in the gender distribution of COVID-19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID-19 patients was 52% (95% CI [0.34,0.70]), and the fatality rate was 5% (95% CI [0.01,0.11]).

Keywords: 2019-nCoV; COVID-19; clinical characteristics; discharge rate; fatality rate; meta-analysis.

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Conflict of interest statement

The authors declare that there are no conflict of interests.

Figures

Figure 1
Figure 1
A flow diagram of the inclusion criteria of studies eligible for meta‐analysis
Figure 2
Figure 2
Forest plot of all the outcomes. (A, C, E) sex distribution; fatality rate; discharge rate. Funnel plot (B, D, F) sex distribution; fatality rate; discharge rate
See this image and copyright information in PMC

Comment in

References

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MeSH terms