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. 1988;26(4):253-6.
doi: 10.1080/02681218880000351.

Increased frequency of HLA-B40 in patients with paracoccidioidomycosis

G B Lacerda  1 , B Arce-Gomez, F Q Telles Filho
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Increased frequency of HLA-B40 in patients with paracoccidioidomycosis

G B Lacerda et al. J Med Vet Mycol. 1988.

Abstract

The presence of 9 HLA-A and 14 HLA-B specificities was determined in 83 patients with paracoccidioidomycosis. The finding of a higher than normal incidence of HLA-B40 (chi 2 = 10.8; corrected P less than 0.026) supports the hypothesis that genetic factors may play a role in susceptibility to paracoccidioidomycosis. The risk of developing paracoccidioidomycosis is 4.3 times higher for individuals carrying HLA-B40 than for those lacking this antigen.

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