All Bacteroides Are Equal but Some Are More Equal than Others For the Induction of IgA
- PMID: 32164843
- DOI: 10.1016/j.chom.2020.02.011
All Bacteroides Are Equal but Some Are More Equal than Others For the Induction of IgA
Abstract
The microbiota is necessary for the induction of intestinal immunoglobulin A (IgA). In this issue of Cell Host & Microbe, Yang et al. (2020) show that the ability to induce or suppress IgA is characteristic of specific strains of Bacteroides ovatus. Immunogenicity and IgA induction by the microbiota is determined by inter-bacterial interaction.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
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Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation.Cell Host Microbe. 2020 Mar 11;27(3):467-475.e6. doi: 10.1016/j.chom.2020.01.016. Epub 2020 Feb 18. Cell Host Microbe. 2020. PMID: 32075742 Free PMC article.
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