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. 2020 Aug:82:104285.
doi: 10.1016/j.meegid.2020.104285. Epub 2020 Mar 10.

Genetic evolution analysis of 2019 novel coronavirus and coronavirus from other species

Chun Li  1 , Yanling Yang  2 , Linzhu Ren  3
Affiliations

Genetic evolution analysis of 2019 novel coronavirus and coronavirus from other species

Chun Li et al. Infect Genet Evol. 2020 Aug.

Erratum in

Abstract

The Corona Virus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a Public Health Emergency of International Concern. However, so far, there are still controversies about the source of the virus and its intermediate host. Here, we found the novel coronavirus was closely related to coronaviruses derived from five wild animals, including Paguma larvata, Paradoxurus hermaphroditus, Civet, Aselliscus stoliczkanus and Rhinolophus sinicus, and was in the same branch of the phylogenetic tree. However, genome and ORF1a homology show that the virus is not the same coronavirus as the coronavirus derived from these five animals, whereas the virus has the highest homology with Bat coronavirus isolate RaTG13.

Keywords: 2019 Coronavirus disease (COVID-19); Genetic evolution; Genome; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Structural protein.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Phylogenetic analysis of coronaviruses from different species and 2019 novel coronavirus in China. The 41 complete genome sequences of coronavirus were analyzed using MEGA 5.0. The phylogenetic tree was constructed using maximum-likelihood (ML) with a bootstrap of 100. Red triangle, SARS-CoV-2 isolate. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
See this image and copyright information in PMC

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