Four Influential Clinical Trials in Human Papilloma Virus-Associated Oropharynx Cancer

Danielle N Margalit¹, Sana D Karam², Melvin L K Chua³, Carryn Anderson⁴, Randall J Kimple⁵

Affiliations

¹ Department of Radiation Oncology, Head and Neck Oncology Program, Dana-Farber/Brigham & Women's Cancer Center, Harvard Medical School, Boston, Massachusetts. Electronic address: danielle_margalit@dfci.harvard.edu.
² Department of Radiation Oncology, University of Colorado School of Medicine, Denver, Colorado.
³ Division of Radiation Oncology and Division of Medical Sciences, National Cancer Centre Singapore, Singapore.
⁴ Department of Radiation Oncology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
⁵ Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

PMID: 32171456
DOI: 10.1016/j.ijrobp.2019.12.015

Comment

Four Influential Clinical Trials in Human Papilloma Virus-Associated Oropharynx Cancer

Danielle N Margalit et al. Int J Radiat Oncol Biol Phys. 2020.

. 2020 Apr 1;106(5):893-899.

doi: 10.1016/j.ijrobp.2019.12.015.

Authors

Danielle N Margalit¹, Sana D Karam², Melvin L K Chua³, Carryn Anderson⁴, Randall J Kimple⁵

Affiliations

¹ Department of Radiation Oncology, Head and Neck Oncology Program, Dana-Farber/Brigham & Women's Cancer Center, Harvard Medical School, Boston, Massachusetts. Electronic address: danielle_margalit@dfci.harvard.edu.
² Department of Radiation Oncology, University of Colorado School of Medicine, Denver, Colorado.
³ Division of Radiation Oncology and Division of Medical Sciences, National Cancer Centre Singapore, Singapore.
⁴ Department of Radiation Oncology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
⁵ Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

PMID: 32171456
DOI: 10.1016/j.ijrobp.2019.12.015

No abstract available

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Comment on

Phase II Evaluation of Aggressive Dose De-Escalation for Adjuvant Chemoradiotherapy in Human Papillomavirus-Associated Oropharynx Squamous Cell Carcinoma.
Ma DJ, Price KA, Moore EJ, Patel SH, Hinni ML, Garcia JJ, Graner DE, Foster NR, Ginos B, Neben-Wittich M, Garces YI, Chintakuntlawar AV, Price DL, Olsen KD, Van Abel KM, Kasperbauer JL, Janus JR, Waddle M, Miller R, Shiraishi S, Foote RL. Ma DJ, et al. J Clin Oncol. 2019 Aug 1;37(22):1909-1918. doi: 10.1200/JCO.19.00463. Epub 2019 Jun 4. J Clin Oncol. 2019. PMID: 31163012 Free PMC article. Clinical Trial.
Phase II Trial of De-Intensified Chemoradiotherapy for Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma.
Chera BS, Amdur RJ, Green R, Shen C, Gupta G, Tan X, Knowles M, Fried D, Hayes N, Weiss J, Grilley-Olson J, Patel S, Zanation A, Hackman T, Zevallos J, Blumberg J, Patel S, Kasibhatla M, Sheets N, Weissler M, Yarbrough W, Mendenhall W. Chera BS, et al. J Clin Oncol. 2019 Oct 10;37(29):2661-2669. doi: 10.1200/JCO.19.01007. Epub 2019 Aug 14. J Clin Oncol. 2019. PMID: 31411949 Free PMC article. Clinical Trial.
A Phase 2 Trial of Alternative Volumes of Oropharyngeal Irradiation for De-intensification (AVOID): Omission of the Resected Primary Tumor Bed After Transoral Robotic Surgery for Human Papilloma Virus-Related Squamous Cell Carcinoma of the Oropharynx.
Swisher-McClure S, Lukens JN, Aggarwal C, Ahn P, Basu D, Bauml JM, Brody R, Chalian A, Cohen RB, Fotouhi-Ghiam A, Geiger G, Gershowitz J, Livolsi V, Mitra N, Montone K, Newman J, Ojerholm E, O'Malley B Jr, Rajasekaran K, Tan E, Weinstein G, Lin A. Swisher-McClure S, et al. Int J Radiat Oncol Biol Phys. 2020 Mar 15;106(4):725-732. doi: 10.1016/j.ijrobp.2019.11.021. Epub 2019 Nov 27. Int J Radiat Oncol Biol Phys. 2020. PMID: 31785337 Clinical Trial.
Correction to Lancet Oncol 2019; 20: 1349-59.
[No authors listed] [No authors listed] Lancet Oncol. 2019 Dec;20(12):e663. doi: 10.1016/S1470-2045(19)30725-9. Lancet Oncol. 2019. PMID: 31797789 No abstract available.

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Four Influential Clinical Trials in Human Papilloma Virus-Associated Oropharynx Cancer

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Four Influential Clinical Trials in Human Papilloma Virus-Associated Oropharynx Cancer

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