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Case Reports
. 2020 Apr;33(4):23-28.
doi: 10.1097/01.JAA.0000657160.48246.91.

A review of Ehlers-Danlos syndrome

Erin Miller  1 , John M Grosel
Affiliations
Case Reports

A review of Ehlers-Danlos syndrome

Erin Miller et al. JAAPA. 2020 Apr.

Abstract

Ehlers-Danlos syndrome (EDS) describes a group of heritable disorders of connective tissue comprising mutations in the genes involved in the structure and/or biosynthesis of collagen. Thirteen EDS subtypes are recognized, with a wide degree of symptom overlap among subtypes and with other connective tissue disorders. The clinical hallmarks of EDS are tissue fragility, joint hypermobility, and skin hyperextensibility. Appropriate diagnosis of EDS is important for correct multidisciplinary management and is associated with better clinical outcomes for patients.

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References

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