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. 2020 May 11;221(11):1770-1774.
doi: 10.1093/infdis/jiaa119.

Clinical Outcomes in 55 Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Who Were Asymptomatic at Hospital Admission in Shenzhen, China

Yanrong Wang  1 , Yingxia Liu  1 , Lei Liu  1 , Xianfeng Wang  2 , Nijuan Luo  2 , Ling Li  2
Affiliations

Clinical Outcomes in 55 Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Who Were Asymptomatic at Hospital Admission in Shenzhen, China

Yanrong Wang et al. J Infect Dis. .

Abstract

An epidemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread unexpectedly in Wuhan, Hubei Province, China, since December 2019. There are few reports about asymptomatic contacts of infected patients identified as positive for SARS-CoV-2 through screening. We studied the epidemiological and clinical outcomes in 55 asymptomatic carriers who were laboratory confirmed to be positive for SARS-CoV-2 through nucleic acid testing of pharyngeal swab samples. The asymptomatic carriers seldom occurred among young people (aged 18-29 years) who had close contact with infected family members. In the majority of patients, the outcome was mild or ordinary 2019 novel coronavirus disease during hospitalization.

Keywords: SARS coronavirus 2; asymptomatic infection; outcome.

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Figures

Figure 1.
Figure 1.
Representative thoracic computed tomographic scans of a patient with severe illness, showing normal findings on admission day 1 (A), diffuse patchy shadowing (arrow) on day 5 (B), more diffuse patchy shadowing (arrows) on day 8 (C), and recovery stage on day 15 (D). R indicated the right lung.
See this image and copyright information in PMC

References

    1. Zhou P, Yang XL, Wang XG, et al. Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin. Nature 2020; 579:270–273.
    1. Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020; 395:514–23. - PMC - PubMed
    1. Phan LT, Nguyen TV, Luong QC, et al. Importation and human-to-human transmission of a novel coronavirus in Vietnam. N Engl J Med 2020; 382:872–4. - PMC - PubMed
    1. Yu P, Zhu J, Zhang Z, et al. A familial cluster of infection associated with the 2019 novel coronavirus indicating possible person-to-person transmission during the incubation period. J Infect Dis. doi: 10.1093/infdis/jiaa077. - DOI - PMC - PubMed
    1. National Health Commission of the People’s Republic of China. National recommendations for diagnosis and treatment of respiratory infections caused by 2019-nCoV (the 6th edition). 18–20 February 2020. Available from: http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aef....

MeSH terms