Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 May;94(5):1769-1770.
doi: 10.1007/s00204-020-02714-5. Epub 2020 Mar 16.

Role of ferroptosis in acetaminophen-induced hepatotoxicity

Affiliations
Comment

Role of ferroptosis in acetaminophen-induced hepatotoxicity

Naoya Yamada et al. Arch Toxicol. 2020 May.
No abstract available

PubMed Disclaimer

Comment in

Comment on

References

    1. Abdel-Azeem AS, Hegazy AM, Ibrahim KS, Farrag AR, El-Sayed EM (2013) Hepatoprotective, antioxidant, and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats. J Diet Suppl 10(3):195–209. https://doi.org/10.3109/19390211.2013.822450 - DOI - PubMed
    1. Abdulkhaleq FM, Alhussainy TM, Badr MM et al (2018) Antioxidative stress effects of vitamins C, E, and B12, and their combination can protect the liver against acetaminophen-induced hepatotoxicity in rats. Drug Des Dev Ther 12:3525–3533. https://doi.org/10.2147/dddt.S172487 - DOI
    1. Amimoto T, Matsura T, Koyama SY, Nakanishi T, Yamada K, Kajiyama G (1995) Acetaminophen-induced hepatic injury in mice: the role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and alpha-tocopherol. Free Radic Biol Med 19(2):169–176. https://doi.org/10.1016/0891-5849(94)00233-a - DOI - PubMed
    1. Bersuker K, Hendricks J, Li Z et al (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature. https://doi.org/10.1038/s41586-019-1705-2 - DOI - PubMed - PMC
    1. Doll S, Freitas FP, Shah R et al (2019) FSP1 is a glutathione-independent ferroptosis suppressor. Nature. https://doi.org/10.1038/s41586-019-1707-0 - DOI - PubMed

LinkOut - more resources