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Comment
. 2020 Jun;200(3):299-301.
doi: 10.1111/cei.13431. Epub 2020 Apr 14.

ELISPOT assays and their diagnostic potential in Lyme disease and Lyme neuroborreliosis

Affiliations
Comment

ELISPOT assays and their diagnostic potential in Lyme disease and Lyme neuroborreliosis

N Ettischer-Schmid et al. Clin Exp Immunol. 2020 Jun.
No abstract available

Keywords: ELISPOT; Lyme borreliosis; T cell assay; interferon-gamma; neuroborreliosis.

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Conflict of interest statement

N. E. S. acts as a paid employee at GenID GmbH and as paid consultant to AID GmbH. R. P. acts as a paid employee at GenID GmbH and as a paid consultant to AID GmbH.

Comment on

References

    1. van Gorkom T, Voet W, Sankatsing SUC et al. Prospective comparison of two enzyme‐linked immunosorbent spot assays for the diagnosis of Lyme neuroborreliosis . Clin Exp Immunol 2020; 199:337–56. - PMC - PubMed
    1. Mygland A, Ljøstad U, Fingerle V et al. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 2010; 17:8–16, e1–4. - PubMed
    1. Hammers‐Berggren S, Hansen K, Lebech AM, Karlsson M. Borrelia burgdorferi‐specific intrathecal antibody production in neuroborreliosis: a follow‐up study. Neurology 1993; 43:169–75. - PubMed
    1. Blanc F, Jaulhac B, Fleury M et al. Relevance of the antibody index to diagnose Lyme neuroborreliosis among seropositive patients. Neurology 2007; 69:953–8. - PubMed
    1. van Burgel ND, Bakels F, Kroes AC, van Dam AP. Discriminating Lyme neuroborreliosis from other neuroinflammatory diseases by levels of CXCL13 in cerebrospinal fluid. J Clin Microbiol 2011; 49:2027–30. - PMC - PubMed