Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Feb 26:15:1-7.
doi: 10.15420/ecr.2019.14.2. eCollection 2020 Feb.

Latest Advances in Cardiac CT

Affiliations
Review

Latest Advances in Cardiac CT

Thomas D Heseltine et al. Eur Cardiol. .

Abstract

Recent rapid technological advancements in cardiac CT have improved image quality and reduced radiation exposure to patients. Furthermore, key insights from large cohort trials have helped delineate cardiovascular disease risk as a function of overall coronary plaque burden and the morphological appearance of individual plaques. The advent of CT-derived fractional flow reserve promises to establish an anatomical and functional test within one modality. Recent data examining the short-term impact of CT-derived fractional flow reserve on downstream care and clinical outcomes have been published. In addition, machine learning is a concept that is being increasingly applied to diagnostic medicine. Over the coming decade, machine learning will begin to be integrated into cardiac CT, and will potentially make a tangible difference to how this modality evolves. The authors have performed an extensive literature review and comprehensive analysis of the recent advances in cardiac CT. They review how recent advances currently impact on clinical care and potential future directions for this imaging modality.

Keywords: CT coronary angiography; Cardiac CT; atherosclerosis; cardiovascular disease risk; coronary artery calcium score; coronary artery disease; fractional flow reserve CT; machine learning.

PubMed Disclaimer

Conflict of interest statement

Disclosure: The authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Example of Non-calcified Plaque with a Calcium Score of Zero
Figure 2:
Figure 2:. An Example of CT-derived Fractional Flow Reserve
Figure 3:
Figure 3:. Multiplanar Reconstruction of the Right Coronary Artery Showing Different Plaque Morphologies and Severe Proximal Stenosis
Figure 4:
Figure 4:. Example of Different Plaque Morphology on Coronary CT
Figure 5:
Figure 5:. Comparison of CT Coronary Angiography Finding to Invasive Coronary Angiography

References

    1. Meijboom WB, Meijs MFL, Schuijf JD et al. Diagnostic accuracy of 64-slice computed tomography coronary angiography. a prospective, multicenter, multivendor study. J Am Coll Cardiol. 2008;52:2135–44. doi: 10.1016/j.jacc.2008.08.058. - DOI - PubMed
    1. Kelion AD, Nicol ED. The rationale for the primacy of coronary CT angiography in the National Institute for Health and Care Excellence (NICE) guideline (CG95) for the investigation of chest pain of recent onset. J Cardiovasc Comput Tomogr. 2018;112:516–22. doi: 10.1016/j.jcct.2018.09.001. - DOI - PubMed
    1. Castellano IA, Nicol ED, Bull RK et al. A prospective national survey of coronary CT angiography radiation doses in the United Kingdom. J Cardiovasc Comput Tomogr. 2017;11(4):268–73. doi: 10.1016/j.jcct.2017.05.002. - DOI - PubMed
    1. British Society of Cardiovascular Imaging, Royal College of Radiologists. Fatal heart conditions going undetected due to lack of scanning services. Nov 8, 2018. https://bsci.org.uk/wp-content/uploads/2019/01/idor_2018_uk_release.pdf (accessed 18 December 2019)
    1. SCOT-HEART Investigators. Coronary CT angiography and 5-year risk of myocardial infarction. N Engl J Med. 2018;379:924–33. doi: 10.1056/NEJMoa1805971. - DOI - PubMed

LinkOut - more resources