Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Feb 25;15(1):159-161.
doi: 10.4103/ajns.AJNS_293_19. eCollection 2020 Jan-Mar.

Adult-Onset Seizure Disorder Secondary to Schizencephaly

Abiodun Idowu Okunlola  1   2 , Paul Olowoyo  3   4 , Cecilia Kehinde Okunlola  3 , Olakunle Fatai Babalola  1   2
Affiliations
Case Reports

Adult-Onset Seizure Disorder Secondary to Schizencephaly

Abiodun Idowu Okunlola et al. Asian J Neurosurg. .

Abstract

Schizencephaly is a very rare neurological disorder usually discovered during radiological evaluation of children and young adults with seizure disorders or neurodevelopmental anomalies. We present a 66-year-old patient with right-sided hemiatrophy and paresis presenting with an adult-onset seizure disorder. Her seizure was satisfactorily controlled with a single-therapy antiseizure drug. Congenital brain lesions should be part of the differential diagnoses in patients with epilepsy who have body asymmetry dated back to childhood.

Keywords: Hemibody atrophy; schizencephaly; seizure disorders.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Right hemibody atrophy
Figure 2
Figure 2
Cranial computed tomography scan showing left parietal open lip schizencephaly
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Granata T, Battaglia G. Schizencephaly. Handb Clin Neurol. 2008;87:235–46. - PubMed
    1. Tietjen I, Bodell A, Apse K, Mendonza AM, Chang BS, Shaw GM, et al. Comprehensive EMX2 genotyping of a large schizencephaly case series. Am J Med Genet A. 2007;143A:1313–6. - PubMed
    1. Mellado C, Poduri A, Gleason D, Elhosary PC, Barry BJ, Partlow JN, et al. Candidate gene sequencing of LHX2, HESX1, and SOX2 in a large schizencephaly cohort. Am J Med Genet A. 2010;152A:2736–42. - PMC - PubMed
    1. Cho WH, Seidenwurm D, Barkovich AJ. Adult-onset neurologic dysfunction associated with cortical malformations. AJNR Am J Neuroradiol. 1999;20:1037–43. - PMC - PubMed
    1. Kamble V, Lahoti AM, Dhok A, Taori A, Pajnigara N. A rare case of schizencephaly in an adult with late presentation. J Family Med Prim Care. 2017;6:450–2. - PMC - PubMed

Publication types