Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar 14;11(3):306.
doi: 10.3390/mi11030306.

2019 Novel Coronavirus Disease (COVID-19): Paving the Road for Rapid Detection and Point-of-Care Diagnostics

Trieu Nguyen  1 , Dang Duong Bang  2 , Anders Wolff  1
Affiliations

2019 Novel Coronavirus Disease (COVID-19): Paving the Road for Rapid Detection and Point-of-Care Diagnostics

Trieu Nguyen et al. Micromachines (Basel). .

Abstract

We believe a point-of-care (PoC) device for the rapid detection of the 2019 novel Coronavirus (SARS-CoV-2) is crucial and urgently needed. With this perspective, we give suggestions regarding a potential candidate for the rapid detection of the coronavirus disease 2019 (COVID-19), as well as factors for the preparedness and response to the outbreak of the COVID-19.

Keywords: (Loop-mediated isothermal amplification) LAMP assay; (polymerase chain reaction) PCR; 2019 novel Coronavirus; COVID-19; Point-of-care detection; SARS-CoV-2; Wuhan.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The illustration for the transmission of coronaviruses and the 2019 novel Coronavirus (2019-nCoV or SARS-CoV-2 [11]). Current studies have suggested that the intermediate carriers may be snakes [12] or pangolins [13], but according to WHO the real source is still unknown [14,15].
Figure 2
Figure 2
The dramatic impact of the rapid detection of infectious diseases in controlling and preventing an outbreak (adapted to WHO document [22] and References [23,24]).
See this image and copyright information in PMC

References

    1. Novel Coronavirus (2019-nCoV), Situation Report 11. [(accessed on 13 March 2020)]; Available online: https://www.who.int/docs/default-source/coronaviruse/situation-reports/2....
    1. Novel Coronavirus ( 2019-nCoV ) Situation Report 48. [(accessed on 13 March 2020)]; Available online: https://www.who.int/docs/default-source/coronaviruse/situation-reports/2....
    1. How 2019-nCoV Spreads. [(accessed on 13 March 2020)]; Available online: https://www.cdc.gov/coronavirus/2019-ncov/about/transmission.html.
    1. Holshue M.L., DeBolt C., Lindquist S., Lofy K.H., Wiesman J., Bruce H., Spitters C., Ericson K., Wilkerson S., Tural A., et al. First Case of 2019 Novel Coronavirus in the United States. N. Engl. J. Med. 2020;382:929–936. doi: 10.1056/NEJMoa2001191. - DOI - PMC - PubMed
    1. Rothe C., Schunk M., Sothmann P., Bretzel G., Froeschl G., Wallrauch C., Zimmer T., Thiel V., Janke C., Guggemos W., et al. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. N. Engl. J. Med. 2020;382:970–971. doi: 10.1056/NEJMc2001468. - DOI - PMC - PubMed

LinkOut - more resources