Context-Dependent Immune Responses Explain Pancreatic Cancer Immunoresistance
- PMID: 32183944
- DOI: 10.1016/j.ccell.2020.02.010
Context-Dependent Immune Responses Explain Pancreatic Cancer Immunoresistance
Abstract
Immunotherapy is standard of care for many malignancies, including non-small cell lung cancer, but its benefits have not extended to pancreatic cancer. In this issue of Cancer Cell, DeNardo and colleagues investigate the differences in immune response in lung and pancreas and potential approaches to overcome immunoresistance in the latter.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
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Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.Cancer Cell. 2020 Mar 16;37(3):289-307.e9. doi: 10.1016/j.ccell.2020.02.008. Cancer Cell. 2020. PMID: 32183949 Free PMC article.
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