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Review
. 2020 Mar 5:12:91-103.
doi: 10.2147/RRU.S232417. eCollection 2020.

Bladder Cancer in Iran: An Epidemiological Review

Khadijeh Kalan Farmanfarma  1 , Neda Mahdavifar  2 , Hamid Salehiniya  3
Affiliations
Review

Bladder Cancer in Iran: An Epidemiological Review

Khadijeh Kalan Farmanfarma et al. Res Rep Urol. .

Abstract

Purpose: Bladder cancer is the sixth most common cancer in Iran. Information about the epidemiological situation of the disease and its risk factors is necessary for conducting a planning program to reduce the disease. This study is conducted with the aim of evaluating the epidemiological features of bladder cancer in Iran.

Methods: This is a systematic review of the published articles in both Persian and English in international and national journals during the years 2000-2019 with key words of Iran and bladder cancer. Articles were selected from the national information database (SID, Magiran) and international databases (PubMed, Scopus, and Web of Science). Articles related to the epidemiological aspects of the disease, including incidence, prevalence, mortality, and risk factors, were evaluated.

Results: The incidence rate of bladder cancer was about 1.6-115; cumulative survival rate was 0.95, mortality rate was 0.5-0.84 and its prevalence in the Iranian population was between 4.10% and 12.8%. The risk of developing malignancy in major risk factor groups, including smoking and opium, was 6.2 (2.04-18.7), increases in protein and animal fat consumption were about 5- and 19-times higher than in the general population, respectively. In terms of occupational exposure, bus and heavy truck drivers were 11.3 (1.3-92.05) more at risk than others.

Conclusion: Regarding the increasing trend of this disease, changes in lifestyle to reduce risk factors can be effective in decreasing the incidence and mortality rate of this malignancy.

Keywords: Iran; bladder cancer; epidemiology; incidence; risk factor.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Flowchart of the included studies in the systematic review.
See this image and copyright information in PMC

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