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Review
. 2018 Sep 27;29(3):127-139.
doi: 10.31138/mjr.29.3.127. eCollection 2018 Sep.

Dry Eye Disease in Routine Rheumatology Practice

Affiliations
Review

Dry Eye Disease in Routine Rheumatology Practice

Sevastiani Ziaragkali et al. Mediterr J Rheumatol. .

Abstract

Dry eye disease (DED) is one of the most frequent ophthalmological conditions, with a major impact on patients' quality of life. Tear film instability and tear hyperosmolarity are considered to play a crucial role in the vicious cycle of dry eye disease. They occur as a result of, either a reduced lacrimal secretion or an excessive evaporation from the tear film. There is a well-known association of DED, not only with autoimmune diseases but also with other systemic diseases and medication. Early diagnosis is important and it is based on the presence of classical symptoms and signs of dry eye in combination with specialized methods. The comprehension of the pathophysiology is significant, as different approaches can be taken to treat DED, depending on the cause and primary source of the disease, as well as on disease severity.

Keywords: Dry Eye Disease; Ocular Surface; Rheumatic Disease; Sjögren’s Syndrome.

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Figures

Figure 1.
Figure 1.
Corneal staining. Superficial Punctate keratitis due to Dry Eye Disease. *Archives of Dr Nikolaos Trakos
Figure 2.
Figure 2.
Staining of the ocular surface with fluorescein in Dry Eye Disease. This patient has blurry vision due to Dry Eye.

References

    1. Dogru M, Foulks GN, Kinoshita S, Laibson P, McCulley J, Murube J, et al. The definition and classification of dry eye disease: Report of the definition and classification subcommittee of the international dry eye workshop (2007). Ocul Surf 2007;5: 75–92. [PMID: ] - PubMed
    1. Akpek EK, Klimava A, Thorne JE, Martin D, Lekhanont K, Ostrovsky A. Evaluation of patients with dry eye for presence of underlying Sjögren syndrome. Cornea 2009;28(5): 493–7. [ 10.1097/ICO.0b013e31818d3846] [PMID: ] - DOI - PMC - PubMed
    1. Craig JP, Nelson JD, Azar DT, Belmonte C, Bron AJ, Chauhan SK, et al. The TFOS DEWS II: Executive Summary. Ocul Surf 2017;15(4): 802–12. [ 10.1016/j.jtos.2017.08.003] - DOI - PubMed
    1. The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop. Ocul Surf 2007;5(2): 93–107. [PMID: ] - PubMed
    1. Galor A, Zheng DD, Arheart KL, et al. Dry eye medication use and expenditures: data from the medical expenditure panel survey 2001 to 2006. Cornea 2012;31(12): 1403–7. [ 10.1097/ICO.0b013e31823cc0b7] [PMID: ] - DOI - PMC - PubMed

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