Surgery as an alternative to radiotherapy in early-stage nasopharyngeal carcinoma: innovation at the expense of uncertainty

Luo Huang^{1

2}, Melvin L K Chua^{1

3

4}

Affiliations

¹ Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, 169610.
² Division of Radiation Oncology, Chongqing University Cancer Hospital and Institute, Chongqing, 400030, P. R. China.
³ Division of Medical Sciences, National Cancer Centre Singapore, Singapore, 169610.
⁴ Oncology Academic Clinical Programme, Duke-National University of Singapore Medical School, Singapore, 169857.

Comment

Luo Huang et al. Cancer Commun (Lond). 2020 Mar.

. 2020 Mar;40(2-3):119-121.

doi: 10.1002/cac2.12015. Epub 2020 Mar 18.

Luo Huang^{1

2}, Melvin L K Chua^{1

3

4}

¹ Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, 169610.
² Division of Radiation Oncology, Chongqing University Cancer Hospital and Institute, Chongqing, 400030, P. R. China.
³ Division of Medical Sciences, National Cancer Centre Singapore, Singapore, 169610.
⁴ Oncology Academic Clinical Programme, Duke-National University of Singapore Medical School, Singapore, 169857.

No abstract available

Keywords: Early stage; nasopharyngeal carcinoma; resection; surgery; toxicities.

Comment on

Minimally invasive surgery alone compared with intensity-modulated radiotherapy for primary stage I nasopharyngeal carcinoma.
Liu YP, Lv X, Zou X, Hua YJ, You R, Yang Q, Xia L, Guo SY, Hu W, Zhang MX, Chen SY, Lin M, Xie YL, Liu LZ, Sun R, Huang PY, Fan W, Guo X, Hong MH, Chen MY. Liu YP, et al. Cancer Commun (Lond). 2019 Nov 15;39(1):75. doi: 10.1186/s40880-019-0415-3. Cancer Commun (Lond). 2019. PMID: 31730020 Free PMC article.

1. Chua MLK, Wee JTS, Hui EP, Chan ATC. Nasopharyngeal carcinoma. Lancet. 2016;387(10022):1012–24. 10.1016/S0140-6736(15)00055-0. - DOI - PubMed
1. Sun XS, Liu SL, Luo MJ, Li XY, Chen QY, Guo SS et al. The association between the development of radiation therapy, IMAGE technology, and chemotherapy, and the survival of patients with nasopharyngeal carcinoma: a cohort study from 1990 to 2012. Int J Radiat Oncol Biol Phys. 2019;105(3):581–90. 10.1016/j.ijrobp.2019.06.2549. - DOI - PubMed
1. Liu LT, Chua MLK, Tao Y, Tang LQ, Mai HQ. Optimal sequencing of chemotherapy with chemoradiotherapy based on TNM stage classification and EBV DNA in locoregionally advanced nasopharyngeal carcinoma. Cancer Commun (Lond). 2019;39(1):64 10.1186/s40880-019-0398-0. - DOI - PMC - PubMed
1. Chen L, Zhang Y, Lai SZ, Li WF, Hu WH, Sun R et al. 10‐Year Results of Therapeutic Ratio by Intensity‐Modulated Radiotherapy Versus Two‐Dimensional Radiotherapy in Patients with Nasopharyngeal Carcinoma. Oncologist. 2019;24(1):e38–e45. 10.1634/theoncologist.2017-0577. - DOI - PMC - PubMed
1. Miao J, Di M, Cao Y, Wang L, Xiao W, Zhu M, et al. Long‐term results of phase II trial of reduced modified clinical target volume in low‐risk nasopharyngeal carcinoma treated with intensity modulated radiotherapy. Annals of Oncology. 2020;30(Supplement 9), November 2019, Page ix99. doi:10.1093/annonc/mdz428.004. - DOI