Focal cemento-osseous dysplasia

Abstract

Focal cemento-osseous dysplasia (FCOD) is a benign fibro-osseous lesion of bone characterized by the replacement of normal bone by fibrous tissue and subsequently followed by its calcification with osseous and cementum-like material. It is mostly asymptomatic in nature and requires no treatment. When secondarily infected, it becomes symptomatic and intervention is required. Here, we report a case of symptomatic FCOD of mandible in a 52-year-old female patient. Histopathological evaluation of the biopsy specimen by ground sections and decalcified sections aided in the final diagnosis of the case.

Keywords: Cementum; decalcification; dysplasia; fibro-osseous; ground section.

Figure 1

Intraoral photograph showing clinically missing 46

Figure 2

Orthopantamogram showing a well-defined radiopaque mass in the right mandible region extending from the distal root of 45 to the mesial root of 47

Figure 3

Photograph showing macroscopic appearance of surgically excised specimen

Figure 4

Photomicrograph of ground section showing the presence of osteons with Haversian canals (low-power magnification)

Figure 5

Low-power magnification of H&E-stained decalcified section showing areas of bone and basophilic globular masses resembling cementum within a delicate fibrocellular connective tissue stroma.

Figure 6

High power magnification of H&E stained decalcified section showing bone with osteocytes within lacunae and delicate fibrocellular connective tissue stroma with vascular spaces

Figure 7

Low-power magnification of H&E-stained decalcified section showing the presence of basophilic globules of cementum, delicate fibrocellular connective tissue stroma with dispersed capillaries