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. 2021:1307:499-519.
doi: 10.1007/5584_2020_515.

Dietary SCFAs Immunotherapy: Reshaping the Gut Microbiota in Diabetes

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Dietary SCFAs Immunotherapy: Reshaping the Gut Microbiota in Diabetes

Yu Anne Yap et al. Adv Exp Med Biol. 2021.

Abstract

Diet-microbiota related inflammatory conditions such as obesity, autoimmune type 1 diabetes (T1D), type 2 diabetes (T2D), cardiovascular disease (CVD) and gut infections have become a stigma in Western societies and developing nations. This book chapter examines the most relevant pre-clinical and clinical studies about diet-gut microbiota approaches as an alternative therapy for diabetes. We also discuss what we and others have extensively investigated- the power of dietary short-chain fatty acids (SCFAs) technology that naturally targets the gut microbiota as an alternative method to prevent and treat diabetes and its related complications.

Keywords: Clinical trials; Diet; Microbiota; SCFAs; T1D; T2D.

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