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1 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: lipengahmu@qq.com.
2 Putuo Center for Disease Control and Prevention, No. 111, Food Factory Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: ptjkfjb@126.com.
3 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 107923738@qq.com.
4 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 86550691@qq.com.
5 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 760510835@qq.com.
6 Putuo Center for Disease Control and Prevention, No. 111, Food Factory Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 514952433@qq.com.
7 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 20531480@qq.com.
8 Putuo Center for Disease Control and Prevention, No. 111, Food Factory Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: zhangzscdc@139.com.
9 Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Rd, 320051, Hangzhou City, Zhejiang Province, China. Electronic address: liushelan@126.com.
10 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: tanganzscdc@126.com.
11 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: zscdc@hotmail.com.
12 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: yanjianbo02@163.com.
1 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: lipengahmu@qq.com.
2 Putuo Center for Disease Control and Prevention, No. 111, Food Factory Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: ptjkfjb@126.com.
3 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 107923738@qq.com.
4 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 86550691@qq.com.
5 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 760510835@qq.com.
6 Putuo Center for Disease Control and Prevention, No. 111, Food Factory Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 514952433@qq.com.
7 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: 20531480@qq.com.
8 Putuo Center for Disease Control and Prevention, No. 111, Food Factory Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: zhangzscdc@139.com.
9 Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Rd, 320051, Hangzhou City, Zhejiang Province, China. Electronic address: liushelan@126.com.
10 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: tanganzscdc@126.com.
11 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: zscdc@hotmail.com.
12 Zhoushan Center for Disease Control and Prevention, No. 568, Wengshan Rd, 316021, Zhoushan City, Zhejiang Province, China. Electronic address: yanjianbo02@163.com.
We report a familial cluster of 2019 novel coronavirus disease (COVID-19) to assess its potential transmission during the incubation period. The first patient in this familial cluster was identified during the presymptomatic period, as a close contact of a confirmed patient. Five family members had close contact with this first patient during his incubation period, with four of them confirmed positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the subsequent sampling tests.
Chan J.F., Yuan S., Kok K.H., To K.K., Chu H., Yang J. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395(10223):514–523. doi: 10.1016/S0140-6736(20)30154-9.
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Li Q., Guan X., Wu P., Wang X., Zhou L., Tong Y. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020;382(13):1199–1207. doi: 10.1056/NEJMoa2001316.
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Tong Z.D., Tang A., Li K.F., Li P., Wang H.L., Yi J.P. Potential presymptomatic transmission of SARS-CoV-2, Zhejiang Province, China, 2020. Emerg Infect Dis. 2020;26(May (5)) doi: 10.3201/eid2605.200198.
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Wang D., Hu B., Hu C., Zhu F., Liu X., Zhang J. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061–1069. doi: 10.1001/jama.2020.1585.
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Yu P., Zhu J., Zhang Z., Han Y., Huang L. A familial cluster of infection associated with the 2019 novel coronavirus indicating potential person-to-person transmission during the incubation period. J Infect Dis. 2020;(February) doi: 10.1093/infdis/jiaa077. pii: jiaa077.
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