Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Aug 1;470(2):304-8.
doi: 10.1016/0165-3806(88)90249-0.

Influence of developmental auditory deprivation on neuronal ultrastructure in the mouse anteroventral cochlear nucleus

D R Trune  1 , C R Morgan
Affiliations

Influence of developmental auditory deprivation on neuronal ultrastructure in the mouse anteroventral cochlear nucleus

D R Trune et al. Brain Res. .

Abstract

Developmental auditory deprivation caused mouse anteroventral cochlear nucleus neurons to have significantly fewer auditory nerve terminals and more non-auditory nerve terminals. This suggested that stimulation regulated the developmental arborization of auditory nerve terminals and competition for synaptic space. Intracellularly, mitochondria were smaller and darker in the deprived neurons and appeared less active metabolically. Interference with these neuronal processes may underlie the impaired development seen in auditory deprivation.

PubMed Disclaimer

Publication types